左氧氟沙星序贯治疗泌尿道感染的经济学评价  

Pharmacoeconomic evaluation of levofloxacin sequential therapy for urinary tract infection

作　　者：沙美娟[1] 

机构地区：[1]南通市第一人民医院药剂科,江苏南通226001

出　　处：《实用药物与临床》2013年第3期227-229,共3页Practical Pharmacy and Clinical Remedies

摘　　要：目的评价左氧氟沙星序贯治疗泌尿道感染的经济学效果。方法 125例泌尿道感染患者随机分为对照组(58例)、序贯治疗组(67例),对照组给予左氧氟沙星注射液400 mg静脉滴注,qd,连用14 d;序贯治疗组先用左氧氟沙星注射液400 mg静脉滴注,qd,连用7 d后改为口服左氧氟沙星片200 mg,bid,连用7 d,观察疗效,并进行最小成本分析。结果对照组与序贯治疗组有效率分别为86.20%和91.04%,两组比较差异无统计学意义(P>0.05)。但对照组最小成本为(903.12±40.75)元,序贯治疗组最小成本为(599.71±36.59)元,对照组明显高于序贯治疗组(P<0.01)。结论左氧氟沙星序贯疗法与单纯静脉滴注相比更经济、安全。Objective To evaluate the pharmacoeconomic efficacy of levofloxacin sequential therapy in the treatment of urinary tract infection（UTI）. Methods 125 patients with UTI were randomly divided into control group（n=58）and sequential therapy group（n=67）.Control group was given levofloxacin injection 400 mg ivgtt（qd） for consecutive 14 d;sequential therapy group was given levofloxacin injection 400 mg ivgtt（qd）for consecutive 7 d,and then changed for levofloxacin tablets 200 mg po（bid） for consecutive 7 d.The clinical efficacy in the two groups was observed and the cost minimization analysis was made. Results The effective rate of control group and sequential group were 86.20% and 91.04%,there was no significant difference between the two groups（P〈0.05）.The cost minimization of control group was（903.12±40.75）yuan,and sequential group was（599.71±36.59）yuan,control group was significantly higher than sequential group（P〈0.01）. Conclusion Compared with using levofloxacin injection alone,the sequential therapy is more economical and safe.

关 键 词：泌尿道感染 左氧氟沙星 序贯疗法 

分 类 号：R691.3[医药卫生—泌尿科学]