红树林内生真菌K38和E33共培养代谢产物研究  

Studys on Metabolites from the Co-culture Broth of Mangrove Endophytic Fungi K38 and E33

作　　者：李春远[1] 龚兵[1] 黄素萍[1] 佘志刚[2] 林永成[2] 周世宁[3] 

机构地区：[1]华南农业大学理学院生物材料研究所,广东广州510642 [2]中山大学化学与化学工程学院,广东广州510275 [3]中山大学生命科学学院,广东广州510275

出　　处：《中山大学学报（自然科学版）》2013年第2期66-69,共4页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：国家863科技攻关计划资助项目(2006AA09Z422;2006AA09Z419);国家自然科学基金资助项目(21102049);广东省自然科学基金资助项目(9451064201003751;9151027501000055);广州市科技计划资助项目(11C12100771);华南农业大学"211工程"三期重点建设项目(2009B010100001);"合生珠江"大学生科技创新实验资助项目(H11005)

摘　　要：将来自南海红树林内生真菌E33和K38的共培养,从该培养液提取物中分离到Castaneiolide(1),脑苷脂-1-O-吡喃葡萄糖基-(2S,3R,4E,2'R)-2-N-(2'-羟基棕榈酰)-9-甲基-4,8-sphingadienine(2),3β,7β,19-三羟基-5-烯-胆甾烷(3),3-羟基-4-(3-甲基-2-丁烯氧)基-苯甲醛(4),对羟基苯甲醛(5)五个代谢产物,其中化合物1,2,4为首次从海洋真菌里得到。化合物1,2,3,4以往未从单独发酵的两菌中分离得到。Two mangrove endophytic fungi K38 and E33 from the South China Sea Coast were co-clutured. Five secondary metabolites, including Castaneiolide（1）,（2S, 3R, 4E,2′R）-2-N-（2′-hydroxy-palmitoyl ）-1-O-β-D-gluco-pyranosyl-9-methyl-4, 8-sphingadienine（2）, cholesta -5-en-3β,7β,19α-triol（3）,3-hydroxy-4-（3-methylbut-2-enyloxy）benzaldehyde （4）,4-hydroxybenzaldehyde（5）, were isolated from this crude extracts. Among them, compounds 1,2,4 were found in marine fungi for the first time, and compounds 1,2,3,4 were not obtained from these two strains by pure fermentation.

关 键 词：红树内生真菌 共培养 代谢产物 

分 类 号：O621.2[理学—有机化学]