过敏性紫癜患儿过敏原检测分析  

Detection of Allergens in Children with Henoch-schonlein Purpura

作　　者：刘静[1] 陆彪[1] 

机构地区：[1]宁夏医科大学总医院儿科,银川750004

出　　处：《宁夏医科大学学报》2013年第2期164-167,F0002,共5页Journal of Ningxia Medical University

摘　　要：目的探讨宁夏地区过敏性紫癜患儿常见食物和吸入性过敏原的检出与分布特征,为过敏性紫癜的预防和治疗提供参考。方法选取2005年11月-2010年11月我院儿科收治的过敏性紫癜患儿849例,应用生物共振治疗仪进行食物和吸入性过敏原检测。结果①过敏性紫癜患儿过敏原阳性率由高到低依次为粉尘螨、豆荚、可可饮料、花草混合物、艾蒿蒿属等。②男女性之间食物及吸入性过敏原阳性率差异均有统计学意义(P<0.05),女孩食物过敏原阳性率高于男孩(P=0.04),男孩吸入性过敏原阳性率高于女孩(P=0.168)。③1～6岁组食物过敏原阳性率高于7～15岁组(P=0.034),差异有统计学意义(P<0.05)。④回族食物过敏原阳性率高于汉族(P=0.007),差异有统计学意义(P<0.01)。⑤不同季节食物及吸入过敏原阳性率差异均具有统计学意义(P=0.000,P<0.01),冬季食物过敏原阳性率最高,夏季吸入性过敏原阳性率最高。结论粉尘螨、豆荚、可可饮料、花草混合物、艾蒿蒿属是宁夏地区过敏性紫癜患儿重要的过敏原。不同性别、年龄、民族及季节在食物和吸入性过敏原阳性率分布上有差异。Objective To detect and analyze allergens with the common seasonal food and inhalant allergens in children with henoch-schonlein purpura（HSP）.Methods 849 children with HSP admitted between November 2005 and November 2010 were recruited in this research.The biological resonance of the common food and inhalant allergens of 849 children were characterized using 2000 German BICOM allergy treatment system.Results ① The top five allergens based on positive rate of allergens for both foods and inhalants in children with HSP were dust mites,pod,cocoa,flowers and artemisia.②The significant difference in food and inhalant allergens was found for both male and female（P0.05）.However,the female had more positive for food allergens（P=0.04）while the male had more positive for the inhalant allergens（P=0.168）.③Food allergens had a significant higher positive rate（P0.05） in aged 1~ 6 than that in aged 7~15.④The food allergens had significantly higher positive rate in Hui ethnicity than that in Han ethnicity（P0.01）.⑤ The food and inhaled allergens shoewed the significantly seasonal difference（P0.01）.The food allergens had the highest positive rate in winter while the inhalant allergens had the highest positive rate in summer.Conclusion In Ningxia,dust mites,pod,cocoa,flowers and Artemisia are the most significant allergens in children who have Henoch-Schonlein purpura.Gender,age,ethnicity,seasonal have impact on the distribution of food,and inhalant allergens.

关 键 词：过敏性紫癜 过敏原 生物共振 儿童 

分 类 号：R725.5[医药卫生—儿科]