野生猕猴应激与抗应激的研究  

STUDY ON STRESS AND ANTI-STRESS OF WILD MACAQUE

作　　者：江燕[1] 张力跃[2] 田保平[2] 王桂兰[2] 

机构地区：[1]云南大学生物系,昆明650091 [2]中国科学院昆明动物研究所

出　　处：《四川动物》2000年第4期224-226,共3页Sichuan Journal of Zoology

基　　金：云南省应用基础研究基金资助项目

摘　　要：本文以野生猕猴为实验对象 ,以血清皮质醇含量为指标 ,研究了野生猕猴被捕获与给予氯丙嗪、Vc 等药物后上述指标的变化。结果表明 :(1)野生猕猴在被捕获后的 1～ 2周内 ,血清皮质醇一直维持在一个高水平状态 (2 4 78± 0 2 0 μg/dl,2 4 88± 0 5 8μg/dl) ;(2 )氯丙嗪可使动物行为处于一种安静状态 ,但并不降低血清皮质醇水平 (2 8 73± 6 16 μg/dl) ,(3)Vc 可改善动物的精神状态 ,使血清皮质醇略低 (2 1 0 0± 2 90 μg/dl) (P >0 0 5 ) ,(4)氯丙嗪和Vc 合用后 ,血清皮质醇与单独使用氯丙嗪无明显差异 (2 8 0 7± 4 45 μg/dl)。Wild macaques under the status of psychological stress and anti stress were investigated.The results were as follows:(1)The concentration of serum cortisone appeared significantly higher after stress (24 78±0 20μg/dl),and it continued in high level for 1～2weeks(24 88±0 58μg/dl)as compared with the normal cortisone level in macaque model(10 78±1 76μg/dl)reported previously by us.(2)Chlorpromazine did not decrease the serum cortisone although it made the animals quiet.(3)Vitamine C lowered the serum cortisone a little and made the animals active.(4)After application of mixture of chlorpromazine and vitamine C,the animal behavior and the serum cortisone did not reveal obvious change as compared with that of single application of chlorpromazine.

关 键 词：野生猕猴 应激 血清皮质醇 防治 

分 类 号：S858.9[农业科学—临床兽医学]