心脏起搏器联合比索洛尔治疗慢快综合征的疗效  

The effects of cardiac pacemaker combing bisoprolol on brady-tachy arrhythmia syndrome

作　　者：吴辉[1,2] 杨俊 丁家望[1,2] 李松 杨简[1,2] 彭家芹 陈勇[1,2] 童晓红 董武松[1,2] 吕志阳 李稳慧[1,2] 

机构地区：[1]三峡大学心血管病研究所 [2]湖北省宜昌市中心人民医院心血管内科,宜昌443003

出　　处：《中国循证心血管医学杂志》2013年第1期38-39,共2页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的评价置入永久性心脏起搏器联合比索洛尔治疗慢快综合征患者的疗效。方法纳入慢快综合征患者45例,均接受永久性心脏起搏器置入并联合比索洛尔治疗,3个月后分析患者临床症状、心电图和超声心动结果对临床疗效进行评价,同时采用SF-36量表对患者生活质量进行评价。结果经永久性心脏起搏器联合比索洛尔治疗后,所有患者与治疗前相比临床症状减轻,严重心律失常发作频率显著下降(心动过缓:48.89%vs.0;心动过速:33.33%vs.0),心率更加平稳[(65.3±7.2)次/分vs.(43.5±6.7)次/分],心功能显著改善[NYHA分级:(1.57±0.42)vs.(2.31±0.35)];SF-36量表评分各项指标均有明显改善(P<0.01)。结论永久性心脏起搏器联合比索洛尔可改善慢快综合征患者预后,提高生活质量。Objective To review the curative effect of permanent cardiac pacemaker combing bisoprolol on brady-tachy arrhythmia syndrome.Methods The patients（n=45） with brady-tachy arrhythmia syndrome were selected and given the implantation of permanent cardiac pacemaker combing bisoprolol treatment.After 3 months,the curative effect was reviewed through counting and analyzing clinical symptoms and results of electrocardiogram（ECG） and echocardiogram.The quality of life in the patients was reviewed by applying SF-36 scale.Results After the treatment,the clinical symptoms were relieved in all patients,seizure frequency of severe arrhythmia decreased significantly（bradyarrhythmia：48.89% vs.0;tachycardia：33.33% vs.0）,heart rate was more smooth [（65.3 ±7.2）vs.（43.5±6.7）],and heart function was significantly improved [NYHA grading：（1.57±0.42）vs.（2.31±0.35）].The scores of SF-36 scale showed all indexes were significantly improved（P0.01）.Conclusion Permanent cardiac pacemaker combing bisoprolol can ameliorate the prognosis and improve the quality of life in the patients with brady-tachy arrhythmia syndrome.

关 键 词：心脏起搏器 比索洛尔 慢快综合征 临床症状 生活质量 

分 类 号：R541.7[医药卫生—心血管疾病]