透析相关性肩关节淀粉样变诊断研究进展  

Advance in the Diagnosis of Dialysis-related Amyloidosis of the Shoulder

作　　者：程强(综述)[1] 黄伟(审校)[1] 

机构地区：[1]重庆医科大学附属第一医院骨科,重庆400016

出　　处：《医学信息》2013年第6期519-520,共2页Journal of Medical Information

摘　　要：血液透析是治疗终末期肾病的主要手段之一，同时也给透析患者带来诸多并发症。其中，透析相关性淀粉样变（dialysis—related amyloidosis，DRA）是其最严重的骨关节系统并发症之一。它主要是由于β2微球蛋白（beta 2-microglobulin，β2-MG）在骨关节系统的沉积所引起。膝关节、髋关节、肩关节及腕关节等是其主要影响的大关节。肩关节是最早受到累及的关节之一，主要表现为肌腱增厚及损伤、关节囊积液及骨质病变等。X线、CT、MRI及放射性核素扫描等均被广泛应用于该病的诊断。本文就透析相关肩关节淀粉样变的诊断进展作一综述。Hemodialysis is a prime approach to treat the last-stage nephropathy, meanwhile it can bring the dialysis patients many complications. One of the most serious complications is dialysis-related amyloidosis. It is main caused by the accumulation of beta 2-microglobulin. The knees, hips, shoulders and wrists all can be involved. One of the earliest affcted joints is the shoulder. Tendon thickening, bursal effusions and bone lesions can be observed. X-ray, CT, MRI and Scintigraphy are all been used to diagnosis this disease. The advances in this field are reviewed in this article.

关 键 词：透析 肩关节淀粉样变 核素扫描 Β2微球蛋白 

分 类 号：R459.5[医药卫生—治疗学]