丹红注射液治疗心肌缺血的疗效评价  

The Evaluation of Danhong Injection on the Treatment of SIM

作　　者：李葵香 冯应君[2] 温景艳 张建勇 唐志英 吴丽华 

机构地区：[1]广东省韶关市第一人民医院 [2]广东省粤北医院 [3]广东省韶关市妇幼保健院,广东韶关512000

出　　处：《赣南医学院学报》2013年第1期74-76,共3页JOURNAL OF GANNAN MEDICAL UNIVERSITY

基　　金：2011年韶关市医药卫生科研计划项目(编号:Y11049)

摘　　要：目的:评价丹红注射液治疗心肌缺血(SMI)的疗效。方法:SMI患者100例,分为对照组和实验组各50例,对照组常规阿司匹林等治疗,实验组用阿司匹林等+丹红注射液治疗,治疗前后分别检测动态心电图(DCG),记录每次SMI发作的最高心率(HMIT)和最低心率(LMIT),及每次缺血发作的持续时间(Tmi)、ST段最大位移(STm)和缺血次数(IN),并计算MIT变异性(Ⅳ)。结果:治疗后两组STm、Tmi、IN、TIB均较用药前明显改善(P<0.05),用药后上述指标间比较,实验组改善更为显著(P<0.05)。治疗后两组的HMIT、LMIT均较用药前提高,而IV较前降低,实验组改变较为显著(P<0.05)。组间比较:IV在用药后两组比较无差异性,而Tmi、TIB在实验组改善较为明显,与对照组相比具有统计学意义(P<0.05)。结论:丹红注射液使用后减少了心肌缺血发作的频率、提高了心肌缺血阈、降低了心肌缺血总负荷(TIB),从而达到有效治疗冠心病SMI的目的。Objective:This paper aims to evaluate Danhong injection on the treatment of SMI.Methods:100 SIM patients were divided into control group and experimental group with 50 in each.Besides regular aspirin treatment given to both groups,Danhong was injected to the experimental group;Prior to and after the medicine,DCG of the subjects was examined,HMIT and LMIT were recorded in case of SMI attack,along with Tmi,STm and IN,subsequently IV of MIT.Results:In terms of the baseline parameter,there exists no statistical difference in both groups.Judging by the index,better results are observed in the experimental group,despite the improvement of STm、Tmi、IN、TIB.HMIT and LMIT of the experimental group and the control group are higher with a lower IV after the treatment with more obvious change in the former(P<0.05).In groups,no difference is observed in IV,but Tmi,STm and TIB of the experimental group are noticeably bettered,thus creating a statistical significance(P<0.05).Conclusion:Danhong injection lessens the frequency of SIM attack,boosts the MIT,lowers TIB of SIM so as to treat more effectively the coronary heart disease of SIM.

关 键 词：心肌缺血阈 丹红注射液 心肌缺血 疗效 

分 类 号：R541.4[医药卫生—心血管疾病]