定量CT对去势兔骨密度观察  

Dynamic observation with QCT on bone mineral density of castrated rabbits

作　　者：韩邕[1] 王桂芝[1] 张光[1] 吕岩[1] 

机构地区：[1]白求恩医科大学第三临床学院放射线科,130031

出　　处：《中国骨质疏松杂志》2000年第3期35-36,共2页Chinese Journal of Osteoporosis

摘　　要：目的　用自制标准件动态观察去势兔的体重、骨密度 ( BMD)。方法　用定量 CT( QCT)方法测量了 18只健康成年雌兔去势前和去势后 5个月、10个月的体重和骨密度。结果　去势后 5个月有61.1%兔体重和 BMD下降 ,而去势后 10个月则 10 0 %体重和骨密度明显下降。结论　 QCT可对临床药物疗效的不同时期进行较精确的数字化动态观察 。Objective To dynamically observe the weight and the bone mineral density(BMD)of the castrated rabbits with a few self made standardized phantoms.Methods Eighteen healthy adult female rabbits were measured for their weight and BMD precastration and 5 and 10 months postcastration with quantitative CT(QCT).Results The weight and BMD decreased in 61.1% of rabbits 5 months after castration and in 100% of rabbits 10 months after the operation.Conclusion QCT can be used to dynamically observe curative effect of drugs in various periods,and it is a good method for studying osteoporosis.

关 键 词：骨质疏松 骨密度 雌激素 

分 类 号：R681.02[医药卫生—骨科学]