血流向量成像技术评价心肌梗死患者左心室舒张功能的研究  

Study of left ventricular diastolic function in patients with myocardial infarction using vector flow mapping

作　　者：张蕾[1] 田家玮[1] 杜国庆[1] 王超[1] 崔浩[1] 刘聪[1] 

机构地区：[1]哈尔滨医科大学附属第二医院超声科,150086

出　　处：《中华超声影像学杂志》2013年第3期190-193,共4页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金（81171404）;教育部高等学校博士学科专项科研基金（20092307110017）;教育部高等学校博士学科点专项科研基金（20102307120012）;黑龙江省自然科学基金项目（D201078）

摘　　要：目的应用血流向量成像（VFM）技术分析心肌梗死患者舒张期左心室血流动力学的变化特征。方法选择临床明确诊断为左室前壁心肌梗死的患者50例作为病例组，另选60例健康体检者作为对照组，比较两组涡流相对于二尖瓣口的横向、纵向位置及圈数，涡流半值面积（s）、涡流直径（D）、涡流最大流量（Qmax）、涡流强度（Qmax／S）。应用组织多普勒测量舒张早期与舒张晚期峰值速度比值（Ea／Aa），并与Qmax／S进行相关性分析。结果①舒张早、晚期，病例组涡流相对于对照组更靠近中线及心尖部，且二尖瓣后叶涡流圈数增多；舒张中期，病例组涡流位置更靠近心尖部，且涡流圈数增多；②病例组与对照组相比，各时期s、D均增大，Qmax／S均减小；舒张早期二尖瓣前叶、舒张中期，病例组Qmax小于对照组，舒张早期二尖瓣后叶、舒张晚期二尖瓣前叶及二尖瓣后叶病例组大于对照组；③Qmax／S与室间隔及侧壁的Ea／Aa呈明显正相关。结论VFM技术够准确反映心肌梗死患者左室心腔内血液流场的结构特征，为心肌梗死患者舒张功能受损程度提供一定的量化指标。Objective To assess the clinical application value of vector flow mapping （VFM） in evaluation of left ventricular diastolic function in patients with myocardial infarction（MI）. Methods Fifty patients with MI were enrolled as patients group. Sixty healthy people were enrolled as control group. The quantitative parameters, including position of vortex, the number of laps, the half-value area （S）, Diameter of half-value area of vortex （D） ,the maximum flow volume of vortex （Qmax） ,and vortex intensity （Qmax/S） were measured in the VFM imaging mode and vortex mode. Difference of the parameters was evaluated between two groups. Ea/Aa were derived via TDI. And correlation analysis was performed between Ea/Aa and Qmax/S. Results Vortex were close to midline and apex cordis. Qmax/S in patients group were decreased,but the number of turns and S and D in patients group were increased. Qmax was changed during different periods of different vortex. Qmax/S had a good correlation with Ea/Aa. Conclusions VFM is a new accurate way for clinical to analysis quantificationally left ventricular blood flow structure and provides quantitative index.

关 键 词：超声心动描记术 心肌梗死 心室功能 左 涡流 

分 类 号：R44[医药卫生—诊断学] R542[医药卫生—临床医学]