对比剂的用量及注射速率对头部多层螺旋CT血管成像质量的影响  

The influence of contrast agent amount and injection velocity on image quality of CT cerebral atery angiography

作　　者：肖正远[1] 戴贵东[1] 兰永树[1] 

机构地区：[1]泸州医学院附属医院CT室,四川泸州646000

出　　处：《实用放射学杂志》2013年第3期451-454,共4页Journal of Practical Radiology

摘　　要：目的 探讨对比剂用量及注射速率对多层螺旋CT脑动脉血管成像质量的影响。方法 采用GE 64层LightSpeed VCT对本院252例临床怀疑或确诊脑血管病患者行CT脑动脉血管造影。将患者随机分为A、B1、B2、C1、C2、D 6组，每组42例，对比剂用量及注射速率分别为A组70 mL、4.0 mL/s， B1组60 mL、4.0 mL/s，B2组60 mL、3.5 mL/s ，C1组50 mL、4.0 mL/s，C2组50 mL、3.5 mL/s，D组40 mL、4.0 mL/s；注射完造影剂后分别用20 mL、30 mL、30 mL、35 mL、35 mL、40 mL生理盐水以相应的速率冲刷。由3位有经验的高级技师双盲法对脑动脉成像质量进行评价。结果 A组与B1组、C1组、D组图像质量经统计学处理（等级资料的两样本秩和检验）P值分别为P〉0.5、0.20.5，差异无统计学意义。结论 64层螺旋CT脑动脉血管成像中，在保证图像质量的前提下可以适当减少对比剂用量及降低注射速率，以减少不良反应的发生率，降低对受检者的危害及减轻患者的经济负担。Objective To evaluate the influence of contrast agent amount and injection velocity on the image quality of multi-slice spiral CT cerebral artery angiography. Methods Cerebral CT angiography was performed in 252 patients with clinically suspected or confirmed cerebrovascular disease using GE 64-slice Light Speed VCT. Patients were divided in six groups based on different contrast agent amount , injection velocity and physiological saline amount as follow ： group A （70 mL , 4.0 mL/s , 20 mL） ,group B1 （60 mL , 4.0 mL/s , 30 mL） , group B2（60 mL , 3.5 mL/s , 30 mL）, group C1 （50 mL,4.0 mL/s,35 mL） ,group C2 （50 mL, 3.5 ml./s,35 mL）, group D （40 mL,4.0 mL/s,40 mL}, each group involved 42 patients. The imaging quality of cerebral artery angiography was evaluated respectively by three experienced radiologists. Results The image quality had no significant difference between group A and group B1, group A and group C1 through two, sample Wilcoxon rank sum test of ranked data statistically,the P values were P〉0.5,0.2〈P〈0.4, respectively;there was significant difference between group A and group D, the P value was P 〈0. 001 ;between group B1 and group B2, group C1 and group C2 had no significant difference , the P values both were P〉0.5 . Conclusion The contrast agent amount and injection velocity can be reduced appropriately ensuring image quality at 64-slice CT cerebral artery angiography,and to reduce the incidence of adverse reactions, the harm to the subjects and to ease the economic burden of patients.

关 键 词：脑 计算机体层成像 脑动脉 血管造影术 对比剂 

分 类 号：R816.1[医药卫生—放射医学] R814.42[医药卫生—临床医学]