肺部真菌感染139例临床分析  

Clinical analysis of 139 cases of pulmonary fungal infection

作　　者：马东波[1] 田蕊[1] 贾要丽[1] 张佳[1] 邝红萍[1] 买佳[1] 王静[1] 

机构地区：[1]郑州大学第一附属医院呼吸与危重症医学科,河南郑州450052

出　　处：《河南医学研究》2013年第1期33-35,共3页Henan Medical Research

基　　金：河南省科技攻关课题(092102300239)

摘　　要：目的:探讨肺部真菌感染发病的临床特征、高危因素、治疗和预后。方法:对139例肺部真茵感染患者的临床资料进行分析。结果:89.2%(124/139)的患者有基础疾病,以慢性阻塞性肺疾病、肺结核、慢性肾病和白血病常见,伴发恶性肿瘤的病人也不少见,原发性肺部真菌感染少见。肺部真菌感染的临床表现无特异性。病原菌主要以酵母菌属为主(62.6%)。早期诊断仍困难。肺部真菌感染病死率较高(7.91%)。结论:多种疾病均可继发真菌感染,其临床表现特异性少,病死率高,应引起临床高度重视。Objective： To summarize the clinical features, therapeutic outcome, prognosis and the major predisposing diseases of pulmonary fungal infection （PFI）. Methods： 139 cases with PFI were retrospectively analyzed. Results ： Various predisposing diseases were found in 89.2% of total cases, among them, COPD, lung tuberculosis, chronic renal disease and leukemia were main predisposing diseases. Primary pulmonary fungal infection was rare. All the clinical manifestations of PFI were not specific. Monilia（Candida） was ranked the first pathogen （62.6%）. The mortality of PFI was high（7.91% ）. Conclusion： Many diseases can be secondary fungus infection. The clinical features of PFI is non-specific and the morbidity is rising. Clinicians should pay more attention to it.

关 键 词：肺部 真菌感染 临床分析 

分 类 号：R563[医药卫生—呼吸系统]