变形杆菌骨伤科感染及药敏分析  

ORTHOPEDIC-TRAUMATOLOGICAL PROTEUS INFECTION AND DRUG SENSITIVE ANALYSIS

作　　者：张玉振[1] 梁建卫 赵云芳 

机构地区：[1]河南省洛阳正骨医院正骨研究所,471002 [2]河南省洛阳市商业储运总公司卫生所

出　　处：《中医正骨》2000年第5期15-16,共2页The Journal of Traditional Chinese Orthopedics and Traumatology

摘　　要：为了加深临床对变形杆菌感染的认识 ,了解该菌的药物敏感情况 ,采用回顾性方法 ,对 1997年 1月～ 1999年 7月骨伤科感染标本中分离出的 2 0 8株变形杆菌 ,结合该院常用的 15种抗生素药敏试验结果进行整理分析 ,结果显示变形杆菌的感染率占12 .4%。其中 ,开放性骨折占 6 5 .4% ,其次为骨髓炎 ,占 2 3.1% ,再次为术后感染 ,占 7.6 %。诺氟沙星、环丙沙星、丁胺卡那霉素、妥布霉素及第 3代头孢菌素是对变形杆菌敏感率高的抗生素。认为变形杆菌感染率有逐年上升趋势 ,应引起临床重视 ;提倡针对药敏试验结果实行用药个体化 ,减少盲目的模式化用药 。WT6BZ]In order to deepen the clinical knowledge of Proteus infection and the understanding of drug sensitive characteristics of bacillus Proteus, 208 strains of Proteus separated from the orthopedic traumatological infected specimens and the results of drug sensitive tests of 15 antibiotics commonly used in the authors hospital were sorted out and analyzed with a retrospective method. The results showed that the Proteus infective rate reached 12.6 %, including 65.4 % in open fracture, 23.1 % in osteomyelitis, 7.6 % in postoperative infection, etc. The antibiotics high sensitive to Proteus included Norfloxacin, Ciproxacin, Amikacin, Tobramycin and Cephalosporins. It was considered that the Proteus infective rate tends to the year by year increase, to which great attention should be paid in the clinical practice, the individualized application of drugs should be recommended and the patternized application of drugs should be decreased as to prevent the new epidemic strain from appearing in a hospital.

关 键 词：变形杆菌 骨伤科感染 抗生素 药敏试验 

分 类 号：R446.5[医药卫生—诊断学]