两种不同手术方式治疗胃十二指肠溃疡急性穿孔的疗效观察  

Effect of two methods on treating acute perforation of gastroduodenal ulcers

作　　者：王时清 

机构地区：[1]广西省柳州市融安县中医医院,广西柳州545400

出　　处：《海南医学院学报》2013年第3期356-358,361,共4页Journal of Hainan Medical University

基　　金：中国高校医学期刊临床专项资金项目(112210557)~~

摘　　要：目的:评估两种不同术式用于治疗胃十二指肠溃疡急性穿孔的临床疗效。方法:将我院收治的92例胃十二指肠溃疡急性穿孔患者,随机分为观察组与对照组,每组46例。观察组给予单纯修补术联合药物治疗,对照组给予胃大部分切除术,观察并比较两组治疗后的疗效。结果:观察组手术时间与住院时间较对照组相比大大缩短,差异有统计学意义(P<0.05)。比较术后1年后两组患者胃酸分泌量,两组患者BAO、MAO与PAO分泌量较术前相比,均有显著降低,但观察组降低幅度明显大于对照组(P<0.05),表明观察组降酸显著,在治疗胃十二指肠溃疡急性穿孔方面更具优势。同时,观察组术后溃疡率为4.35%,并发症发生率为13.04%,而对照组溃疡复发率为26.09%,术后并发症发生率为39.13%,表明观察组预后良好。结论:单纯修补术联合药物治疗较胃大部分切除术降酸显著,操作简单,溃疡复发率与并发症发生率大大降低,具有显著优势,是临床治疗的胃十二指肠溃疡急性穿孔首选方法。Objective： To investigate the effect of two operations on treating acute perforation of gastroduodenal ulcers. Methods： A total of 92 cases with acute perforation of gastroduodenal ulcers in our hospital were divided into the observation group and the control group. Patients in observation group received the treatment of simple kposthesis combined with pharmacotherapy and the control group received the treatment of stomach premodinantly ablation. The efficacy was compared. Results= After surgery, the time of operation and and length of stay in the observation group were significantly shortened compared with control group （P〈0. 05）. The level of BAO, MAC and PAO were significantly lower than those in control group （P〈0. 05）. The recurrence rate was 4. 35%, and the complication rate of ulcer was 13.04%in observation group; While the recurrence rate and complication rate of control group was 26.09 Mand 39.13 %. Conclusions：Simple kposthesis is effective on treating acute perforation of gastroduodenal ulcers. It is easy to operate and of low recurrence and complication incidence, so it is preferred way for treating acute perforation of gastroduodenal ulcers.

关 键 词：单纯修补术 胃十二指肠溃疡 急性穿孔 

分 类 号：R656.62[医药卫生—外科学]