随机、对照评价对心力衰竭疾病患者的近期和远期疗效比较  

Randomized,controlled evaluation of recent and long-term benefits for patients with chronic heart failure

作　　者：陈楠楠[1] 王渊铭[1] 姚建华[1] 苏枫[1] 黄晴[1] 

机构地区：[1]上海市杨浦区中心医院心内科,上海200090

出　　处：《四川医学》2013年第2期256-257,共2页Sichuan Medical Journal

摘　　要：目的探讨美托洛尔在慢性充血性心力衰竭的相关作用,随机、对照评价对心力衰竭患者疾病管理的近期和远期效益。方法对70例慢性心力衰竭患者一组使用利尿药物如呋塞米和洋地黄类药物做一治疗,为对照组;另一组在前一组治疗的基础上服用β受体阻滞剂美托洛尔。12周后,比较和分析两组最终治疗的相关指标有无区别和变化。结果采用美托洛尔治疗的观察组其总有效率比利用常规方法治疗的对照组要高出较多,差异有统计学意义(P<0.05);而观察组的各疗效指标变化情况较对照组明显改善(P<0.05)。结论美托洛尔在慢性心力衰竭疾病时,效果十分明显,在临床上的认可程度高,值得进一步的推广和应用。Objective To investigate the clinical efficacy of metoprolol in treatment of chronic heart failure.Methods 70 patients with chronic heart failure were randomly divided into control group and observation group,both were 35 cases.The control group was treated with diuretics,digitalis and angiotensin-converting enzyme inhibitor drugs while observation group was treated with metoprolol based on the control group.Results The total effective rate of observation group was 85.7% higher than the control group（68.6%）,and the difference was statistically significant（P〈0.05）;after treatment,the heart indicators in observation group were better than the control group,and the differences were statistically significant（P〈0.05）.Conclusion Metoprolol in treatment of chronic heart failure with good effect,can effectively improve patients＇ life quality.

关 键 词：充血性心力衰竭 美托洛尔 疗效 

分 类 号：R541.62[医药卫生—心血管疾病]