两种不同方法检测变应性鼻炎过敏原的对比研究  

Comparison between two different detection methods of allergen in patients with allergic rhinitis

作　　者：李莹[1] 马瑞霞[2] 

机构地区：[1]宁夏医科大学,宁夏银川750004 [2]宁夏医科大学总医院耳鼻咽喉头颈外科,宁夏银川750004

出　　处：《宁夏医学杂志》2013年第3期229-230,共2页Ningxia Medical Journal

摘　　要：目的用生物共振过敏原检测法和皮肤点刺法对变应性鼻炎患者的变应原一致性进行对比观察。方法对32例变应性鼻炎患者的320项过敏原进行生物共振过敏原检测和皮肤点刺检测,将两种方法的检测结果进行一致性检验。结果 32例患者中生物共振法及皮肤点刺法的阳性患者检出率分别为62.50%和81.25%,两种方法均为阳性20例,两者一致性较好(Kappa=0.56>0.4);320项检测中,生物共振法及皮肤点刺法过敏原检出率分别为43.52%和60.00%,两种方法均为阳性的133项,两者一致性较好(Kappa=0.62>0.4)。结论生物共振检测与皮肤点刺法过敏原检测一致性较好,生物共振检测可辅助临床应用,但是否为判定变应性鼻炎的金标准还需进一步的实验证明。Objective To study the consistency of the two methods, MORA - Super Bioresonance and skin prick test, in chec- king the allergens in patients with allergic rhinitis. Methods A clinical trial was conducted in 32 suspected patients with allergic rhini- tis. All patients accepted MORA - Super Bioresonance and skin prick test to the same 10 kinds of allergens. Then the checking result and consistency were compared. Results The detection rates of allergen were 62.50% and 81.25% in 32 suspecting patients by using MORA - Super Bioresonance method and using skin prick test method, there was a good consistency （ Kappa = 0.56 〉 O. 4） ; the detec- tion rates of allergen were 43.52% and 60.00% in 32 suspecting patients by using MORA - Super Bioresonance method and using skin prick test method, there was a good consistency too （ Kappa = 0.62 〉 0.4）. Conclusion There is a good consistency between MORA - Super Bioresonance method and skin prick test method, but there is still a certain gap on the accuracy comparing with the gold standard. So the MORA -Super Bioresonance method can be used to assist the clinical therapy, but whether it can be used as a gold standard to the allergic rhinitis diagnosis is also need to be proved in the future.

关 键 词：变应性鼻炎 过敏原检测 皮肤点刺 生物共振 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]