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机构地区:[1]广州医学院附属广州市妇女儿童医疗中心 [2]广州市儿童医院儿科,广东省广州市510623 [3]华南理工大学电子商务系
出 处:《中国全科医学》2013年第9期997-1000,共4页Chinese General Practice
基 金:广东省医学科学技术研究基金面上项目(A2010472);广州市妇女儿童医疗中心博士启动基金项目(201008);教育部青年基金项目(10YJC630236);中央高校基金项目(2011ZM0080)
摘 要:目的探讨广义规则归纳(GRI)算法在肺炎患儿临床特征与病原关联研究的应用价值。方法以2005—2009年广州市儿童医院住院的6 290例肺炎患儿临床资料作为基础,运用GRI算法分析肺炎患儿临床特征与不同病原的关联。结果住院肺炎患儿中喘息性支气管肺炎2 095例,占33.31%;呼吸道合胞病毒肺炎1 377例,占21.89%;支原体肺炎1 221例,占19.41%。男性和女性患儿关联度最高的均是喘息性支气管肺炎和呼吸道合胞病毒肺炎。婴儿期(0岁<年龄≤1岁)和幼儿期(1岁<年龄≤3岁)患儿关联度最高的是喘息性支气管肺炎和呼吸道合胞病毒肺炎;学龄前期(3岁<年龄≤6岁)和学龄期(6岁<年龄≤14岁)患儿关联度最高的均是支原体肺炎。2005年关联度最高的是喘息性支气管肺炎和支原体肺炎;2006年关联度最高的是喘息性支气管肺炎和呼吸道合胞病毒肺炎;2007年和2008年关联度最高的均是呼吸道合胞病毒肺炎;2009年关联度最高的是流行性感冒病毒肺炎。结论GRI算法可以探索肺炎患儿临床特征与不同病原之间的多重相关性,为肺炎患儿临床防治工作提供新的依据。Objective To explore the application of generalized rule induction (GRI) association rules on the relation- ship between pneumonia clinical features and the pathogens of pneumonia in children. Methods GRI association rules were used to analyze the relationship between pneumonia clinical features and the pathogens of pneumonia in 6 290 pneumonia children ad- mitted to Guangzhou Children's Hospital from 2005 to 2009. Results Among the pneumonia children, 2 095 cases were asthmat- ic bronchopneumonia, accounting for 33.31%; 1 377 cases were respiratory syncytial virus pneumonia, accounting for 21.89% ; 1 221 cases were mycoplasmal pneumonia, accounting for 19. 41%. Asthmatic bronchopneumonia and respiratory syn- cytial virus pneumonia had the highest association degree respectively among boys and girls. For infants ( aged from 0 to 1 ) and toddlers ( aged from 1 to 3 ), asthmatic bronchopneumonia and respiratory syncytial vires pneumonia had the highest association degree, and for pre -school age child (aged from 3 to 6) and school age child (aged from 6 to 14) , mycoplasmal pneumonia had the highest association degree. From 2005 to 2009, asthmatic bronchopneumonia and respiratory syncytial virus pneumonia (2005), asthmatic bronchopneumonia and respiratory syncytial virus pneumonia (2006), respiratory syncytial virus pneumonia (2007, 2008) and influenza virus pneumonia (2009) had highest association degree respectively. Conclusion GRI association rule can be adopted to analyze the relationship between the pneumonia clinical features and the pathogens of pneumonia in children, thus providing new reference for pneumonia prevention and control in children.
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