基于STATA固尔苏治疗肺透明膜病的系统评价  

Systematic Evaluation of Curosurf for Treating Hyaline Membrane Disease Using STATA

作　　者：陈友生[1] 余超[2] 胡炜华[3] 

机构地区：[1]中国人民解放军第九四医院信息科,南昌330002 [2]南昌大学研究生院医学部,2010级南昌330006 [3]南昌大学期刊社,南昌330006

出　　处：《南昌大学学报（医学版）》2013年第1期26-29,共4页Journal of Nanchang University：Medical Sciences

摘　　要：目的基于STATA对固尔苏治疗肺透明膜病的疗效进行系统评价。方法通过Cochrane图书馆(2011年第4期)的临床对照试验中心资料库、PubMed、万方、维普、CNKI及中国生物医学文献系统(手工检索新生儿疾病会议论文和内部资料等灰色文献)检索固尔苏治疗肺透明膜病的随机对照试验文献。利用Revman 5.1.4.0软件进行Meta分析,并用STATA12.0软件进行发表偏倚的评价。结果共纳入10篇中文文献。合并分析结果显示,固尔苏治疗组治疗28d内的病死率与对照组相比,差异有统计学意义(RR=0.35,95%CI0.23～0.54)。结论固尔苏能降低肺透明膜病的病死率,对治疗肺透明膜病有一定的疗效。Objective To systematically evaluate the effect of Curosurf on hyaline membrane disease using＇STATA. Methods The literature was searched for randomized controlled trials ofCurosurf to treat hyaline membrane disease using central repository in controlled clinical trials of controlled clinical trials （Cochrane Collaboration, No. 4,2011）, PubMed, Wanfang Data, CQVIP,CNKI and CBMD ISC. Revman 5.1.4.0 software was used to perform Meta-analysis and STATA12.0 software was used to evaluate publication bias. Results A total of 10 Chinese literatureswere collected. The combined analysis results showed that Curosurf treatment （〈28 days） significantly decreased the mortality compared with control group（RR=0.35,95 % CIO. 23-0.54）. Conclusion The treatment with Curosurf can reduce the mortality and may have a demonstrable curative effect on hyaline membrane disease.

关 键 词：肺透明膜病 固尔苏 系统评价 META分析 STATA软件 

分 类 号：R722.1[医药卫生—儿科]