金纳米粒子聚集体系的制备及其SERS效应表征  

Preparation of Gold Nanoparticle Aggregates and Characterization for Their SERS Effect

作　　者：李玲[1] 曹晓卫[1] 李欣然[1] 张志学[1] 冯小平[1] 

机构地区：[1]上海师范大学化学系,上海200234

出　　处：《光散射学报》2013年第1期29-34,共6页The Journal of Light Scattering

基　　金：国家自然科学基金(20775049;20973114);上海市自然科学基金项目;上海市教委科研创新项目

摘　　要：以Na2S作为金纳米粒子的还原制备与聚集剂制备了金纳米粒子聚集体系。在制备过程中通过紫外可见光谱对制备条件进行了优化。TEM表征显示聚集体系中的金纳米粒子均为球形,且聚集状态呈现出较好的均匀性。将这一聚集体系作为SERS基底应用于若干氨基酸分子的SERS光谱表征与分析。初步的研究表明Na2S-金纳米粒子聚集体系可有效地应用于生物分子的SERS光谱表征与分析。This article used Na2S as a chemical reduction and aggregation agent to prepare unique gold nanoparticle aggregates under the roomtemperature condition. By ultraviolet visible spectroscopy, the preparation procedure and technological conditions were opti mized for the purpose of preparation of steady aggregates. The transmission electron mi croscopic images display that the asprepared gold nanoparticles are spherical and the gold nanoparticles are gathered so effectively that these particles can finally form welldefined aggregates. Furthermore, the asprepared aggregates were used as the substrates of sur faceenhanced Raman scattering （SERS） measurements to characterize several amino acid molecules such as glycine and histidine. Previous investigations show that the asprepared gold nanoparticle aggregates possess so good SERS activity and this make it useful for SERS analysis of a wide variety of biomolecules.

关 键 词：金纳米粒子聚集体 硫化钠 表面增强拉曼光谱 甘氨酸 组氨酸 

分 类 号：O648.15[理学—物理化学]