ST59型社区获得性耐甲氧西林金黄色葡萄球菌毒力因子研究  

ST59 Type Community Acquired Methicillin Resistant Staphylococcus aureus Virulence Factors

作　　者：陈咏君[1,2] 田素飞[1] 褚云卓[1] 郭丽洁[1] 丁丽萍[1] 李富顺[1] 

机构地区：[1]中国医科大学附属第一医院检验科,辽宁沈阳110001 [2]沈阳医学院附属沈洲医院检验科,辽宁沈阳110001

出　　处：《微生物学杂志》2013年第1期71-74,共4页Journal of Microbiology

摘　　要：了解ST59型社区获得性耐甲氧西林金黄色葡萄球菌(community-acquired methicillin-resistant Staphy-lococcus aureus,CA-MRSA)携带毒力因子的情况。用PCR方法扩增ST59型CA-MRSA PSMα、PVL、SEA、SEB、SEC、SED、SEE、TSST-1、ETA、ETB基因。5株CA-MRSA全部检出PSMα基因和PVL基因,均未检出SEA、SEB、SEC、SED、SEE、TSST-1、ETA、ETB基因。PSMα和PVL基因是ST59型社区获得性耐甲氧西林金黄色葡萄球菌常见的毒力因子。In order to understand virulence factors carrying case of ST59 type community acquired methieillin resistant S. aureus （CA-MRSA） , PSMα, PVL, SEA, SEB, SEC, SED, SEE, TSST-1, ETA, and ETB genes of ST59 type were amplified by PCR. The results showed that 5 strains of ST59 CA-MRSA were all detected PSMα and PVL genes, however, SEA, SEB, SEC, SED, SEE, TSST-1, ETA, and ETB genes were not detected. Therefore, PSMct and PVL genes were common virulence factors of ST59 type CA-MRSA.

关 键 词：ST59 社区获得性耐甲氧西林金黄色葡萄球菌 α型苯酚可溶解的调控蛋白 杀白细胞素 

分 类 号：R378.11[医药卫生—病原生物学]