中药加味桔梗汤防治放射性食管炎80例临床观察  

The Clinical Therapeutic Effect of Modified Platycodon Grandiflorum Decoction on 80 Cases of Radioactive Esophagitis

作　　者：周映伽[1] 黄杰[1] 沈红梅[1] 

机构地区：[1]昆明医科大学第三附属医院,云南省肿瘤研究所中西医结合肿瘤临床研究中心,云南昆明650118

出　　处：《昆明医科大学学报》2013年第1期68-70,88,共4页Journal of Kunming Medical University

基　　金：云南省自然科学基金资助项目(2009CD182);云南省教育厅科学研究基金资助项目(2010Y186;07Y10626);云南省卫生厅科技计划资助项目(2009NS022)

摘　　要：目的探讨中药加味桔梗汤防治急性放射性食管炎的疗效.方法将80例入选患者随机分为对照组与治疗组,每组各40例.放疗期间对照组采用蒙脱石散口服,治疗采用中药加味桔梗汤缓慢吞服.观察两组病例放射性食管炎发生率,于DT0、20、30、40、50 Gy及放疗结束时,分度记录放射性食管炎症状;放疗结束后,进行放射性食管炎临床症状及内镜观察情况分级评价.结果治疗组放射性食管炎发生率67.5%.对照组放射性食管炎发生率92.5%.治疗组有效率为95%,对照组有效率为62.5%.两者相比差异有统计学意义(P<0.05).结论中药加味桔梗汤可有效防治急性放射性食管炎.Objective To observe the clinical therapeutic effect of Modified Platycodon grandiflorum Decoction on radioactive esophagitis.Metheds 80 selected patients were divided into two groups randomly and averagely：during radiotherapy,patients in the control group were treated by Montmorillonite powder,and patients in the treatment group took the Modified Platycodon grandiflorum Decoction.The incidence rate of radioactive esophagitis after radiotherapy was recorded.Results 67.5% of patients suffered from radioactive esophagitis in treatment group and 92.5% in control group.The effective rate was 95% in treatment group and 62.5% in control group.There were significant difference between two groups.Conclusion The Modified Platycodon grandiflorum Decoction could effectively prevent and cure radioactive esophagitis.

关 键 词：加味桔梗汤 放射性食管炎 内镜 

分 类 号：R658[医药卫生—外科学]