MRS与DWI对前列腺中央腺体癌的诊断价值  

The value of magnetic resonance spectroscopy and diffusion weighted imaging in evaluation of prostatic central gland cancer

作　　者：李秀燕[1,2] 李燕[3] 张洁[1] 袁宪顺[1] 刘庆伟[1] 

机构地区：[1]山东大学附属省立医院医学影像科,山东济南250021 [2]山东省荣军总医院放射科,山东济南250013 [3]山东省医学影像学研究所,山东济南250021

出　　处：《医学影像学杂志》2013年第3期442-445,共4页Journal of Medical Imaging

基　　金：山东省自然科学基金项目(Y2008C108)

摘　　要：目的探讨3D1 H MR波谱(MRS)分析和扩散加权成像(DWI)对前列腺中央腺体癌的检出价值。方法对55例前列腺中央腺体疾病的患者行MRS和扩散加权成像(DWI)扫描,经穿刺活检证实,15例为前列腺癌(PCa),40例为前列腺增生(BPH),比较两组间的(胆碱+肌酸)/枸橼酸盐(CC/C)值和表观扩散系数(ADC)值。结果 PCa组和BPH组的CC/C值分别为2.93±1.77和0.67±0.39,PCa组和BPH组的ADC值分别为(0.71±0.32)×10-3 mm2·s-1和(1.21±0.26)×10-3 mm2·s-1,PCa组和BPH组之间的CC/C值和ADC值差异均有统计学意义(P<0.05)。结论 MRS和DWI对前列腺中央腺体癌的诊断具有一定价值。Objective To investigate the clinical value of magnetic resonance spectroscopy and diffusion-weighted imaging in detection of prostatic central gland cancer. Methods The clinical and imaging data of 55 patients were analyzed retrospectively, including 15 cases with prostatic central gland cancer and 40 cases with benign prostatic hyperplasia （BPH）, the CC/C values and ADC values of the two groups were compared. Results The mean CC/C value of the PCa and the BPH were 2.93!1.77 and 0.67±0.39, respectively, while the minimal ADC value of the PCa and the BPH were （0.71 ±0.32） X 103 mm2 / s and （1.21±0.26） X 10-3 mm2 / s, respectively. Statistically significant difference was analysed between the two groups （ P d0.05） . Conclusion MRS and DWI are helpful in the differential diagnosis of prostatic central gland cancer.

关 键 词：前列腺癌 磁共振成像 磁共振波谱分析 扩散加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]