人骨拉伸和压缩力学的性能测试  

Tensile and compressive mechanical property of human bone tissue

作　　者：王尚城[1] 王冬梅[1] 汪方[2] 王秋根[2] 王春慧[3] 陈善广[3] 

机构地区：[1]上海交通大学机械与动力工程学院,上海市200240 [2]上海交通大学医学院附属第一人民医院,上海市200240 [3]中国航天员训练中心,北京市100094

出　　处：《中国组织工程研究》2013年第7期1180-1184,共5页Chinese Journal of Tissue Engineering Research

基　　金：国家重点基础研究发展计划(973计划)(2011CB711000);国家自然科学基金资助项目(81071234);上海市松江区卫生局经费资助项目(2011LX14)~~

摘　　要：背景:人体骨组织材料力学性能参数是进行骨骼内部应力计算分析、断裂损伤分析、应力骨改建研究等的基础数据,也是深入开展人体骨骼生物力学行为特性研究的必要已知条件之一,但目前国际上还没有统一的骨组织力学性能测试的试验标准。目的:探讨骨组织拉压力学性能测试的试样制备、试样约束和夹持、试验数据处理和试验误差等问题的研究进展。方法:在骨组织拉伸压缩试验无具体标准可循的环境下,对已验证的试验方法和途径进行介绍。总结并强调了骨组织拉压试验中的各项误差及其减少;以减少系统误差为目的,介绍了规范的骨组织宏观拉压测试方法。结果与结论:通过拉伸压缩试验可获得骨组织的弹性模量、泊松比、拉伸强度和压缩强度等重要力学性能参数,测试关键环节涉及标准试样设计和加工、试件夹持、试验数据处理和力学参数的计算,各环节均需参照最新研究以减少试验误差。BACKGROUND： The mechanical parameters of human bone tissue materials are not only the fundamental data for the stress calculation, fracture damage analysis and stress-related bone remodeling, but also one of the main indispensable factors for the further investigation of the characteristics of biomechanical behavior of human bone. However, no international standards for the bone mechanical property tests have been reported.OBJECTIVE： To summarize the research progress on the topics of specimen preparation, specimen constraints and fixation, test data processing and experiment error of tension-compression testing. METHODS： Under the environment of no specific standard for the tensile and compression testing of bone tissue to follow, the verified test methods and ways were introduced. The error and its decrease during the tension-compression testing were concluded and emphasized; the standardized bone tissue macro tension and compression test method was also introduced with the purpose of reducing the systematic errors. RESULTS AND CONCLUSION： By performing the tension-compression testing, key parameters such as elastic modulus, Poisson＇s ratio, tensile strength and compress strength of the bone tissue could be acquired. Important testing procedures involving designing and machining of standard specimen, specimen gripping, data processing and mechanical parameter calculation were tested. During each procedure, the systematic errors need to be reduced according to the latest researches.

关 键 词：组织构建 组织构建与生物力学 皮质骨 松质骨 力学性能 测试 生物力学 国家自然科学基金 

分 类 号：R318[医药卫生—生物医学工程]