生物电化学仪器的发展现状与展望  

Current Statuses and Prospects of Bioeletrochemical Instruments

作　　者：胡仁[1] 朴春晖 林昌健[1] 詹东平[1] 任斌[1] AMATORE Christian 田中群[1] 

机构地区：[1]厦门大学固体表面物理化学国家重点实验室,化学化工学院,XiamENS中法联合实验室,福建厦门361005 [2]法国巴黎高等师范学校化学系,法国巴黎75231

出　　处：《电化学》2013年第2期97-102,共6页Journal of Electrochemistry

基　　金：国家重点基础研究发展计划资助项目(No.2007CB935603);国家自然科学基金-重大国际合作研究资助项目(No.20620130427);科技部-国际科技合作资助项目(No.2007DFC40440)资助

摘　　要：电荷传递是生命运动的基本过程之一,电化学方法在生命科学中的应用为相关生命现象的研究提供了一个有效而独特的物理化学视角,并带来超出常规生物学检测的丰富信息.随着生物电化学研究的不断扩展和深化,已从早期的生物分子电化学研究深入向活体、活细胞、单活细胞水平甚至活细胞中单分子水平发展.研究者对仪器设备性能如灵敏度、分辨率(时间分辨、空间分辨和能量分辨)和操作性等提出了越来越高的要求.本文综述了生物电化学仪器在应用领域和研究领域的现状,重点介绍单细胞电化学检测系统的构建,并初步探讨国内生物电化学研究仪器的发展趋势.Charge transfer is one of the essential life processes. In the past decades, the electrochemical methods have been developed to study life science in a unique physicochemical view and have exhibited abundant and precious information beyond conventional biological techniques. As bioelectrochemical research areas evolved from the fundamental studies of biomolecules＇ electrochemical behaviours in non-living conditions to the living cells in intro and in vivo, and further to the single molecule in living systems, the role of instruments becomes more and more crucial. The performances of instruments such as sensitivity, resolution （time, spatial and eneygy resolutions） and controllability are more demanding in the living conditions and at small size. In this review, the current statuses of the bioelectrochemical instruments, especially those for electrochemical studies at single living cell level, are presented; and the prospects of the domestic bioelectrochemical instruments are discussed.

关 键 词：生物电化学仪器 单活细胞 

分 类 号：O657.1[理学—分析化学]