加巴喷丁预给药对上肢手术止血带反应的影响  

Effect of preoperative application with gabapentin on tourniquet reaction during upper extremity surgery

作　　者：漆升 李茂兵[1] 吴新勤 

机构地区：[1]浙江省建德市第一人民医院麻醉科,311600

出　　处：《实用医学杂志》2013年第7期1154-1156,共3页The Journal of Practical Medicine

摘　　要：目的:观察术前应用加巴喷丁对腋路臂丛神经阻滞下上肢手术止血带反应的影响。方法:择期行上肢肘关节以下手术患者80例随机分为G组(术前1h服用加巴喷丁300mg)和C组(安慰剂组),每组各40例。比较两组间止血带反应例数、止血带反应发生时间、止血带反应程度(视觉模拟评分,VAS)、术中需辅助芬太尼的剂量及止血带反应时血流动力学指标。结果:G组与C组在止血带反应例数、止血带反应发生时间、止血带反应程度、术中辅助芬太尼的剂量及止血带反应时血流动力学改变方面差异均有统计学意义(P<0.05)。结论:术前1h口服加巴喷丁300mg可以降低腋路臂丛神经阻滞下上肢手术止血带反应的发生率及严重程度。Objective To observe the effect of preoperative application with gabapentin on tourniquet reaction during upper extremity surgery. Methods Eighty patients undergoing upper extremity surgery were randomly and equally allocated into two groups： test group （gabapentin） and control group （placebo）. Each of them were recorded the following items： tourniquet reaction occurring time, tourniquet reaction degree （visual analogue scale, VAS）, fentanyl dose intraoperative required and hemodynamie index. Results Cases of tourniquet reaction, tourniquet reaction degree, fentanyl dose intraoperative required and hemodynamic change in test group were significantly lower than those of in control group （P 〈 0.05）. Conclusion Preoperative application with gabapentin can reduce the tourniquet reaction during upper extremity surgery.

关 键 词：加巴喷丁 臂丛 止血带反应 

分 类 号：R614[医药卫生—麻醉学]