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作 者:周怀远[1] 廖伟强[1] 陈莞春[1] 段学蕴[1]
出 处:《国际医药卫生导报》2013年第6期750-753,共4页International Medicine and Health Guidance News
基 金:广东省东莞市科技计划医疗卫生类科研项目(2010105150081)
摘 要:目的利用超声二维斑点追踪技术探讨母亲妊娠期糖尿病对其所生的新生儿心脏结构和功能的影响。方法观察组妊娠期糖尿病母亲所生新生儿45例,正常对照组新生儿45例。超声心动图检查,观察新生儿心脏结构,测量左心室壁厚度,采集胸骨旁左室短轴乳头肌水平3个心动周期的动态图像,并应用二维斑点追踪技术计算新生儿左心室扭转角度。结果观察组室间隔舒张厚度(0.45±0.06)cm,对照组(0.34±0.05)cm观察组左室后壁舒张厚度(0.45-±0.17)cm,对照组(0.31±0.02)cm。观察组左室内膜旋转峰值为(-4.713±2.049)°,对照组为(-3.744±1.854)°;观察组左室平面旋转峰值为(-2.351±1.429)°,对照组为(-1.413±0.918)°;观察组左室外膜旋转峰值为(-1.457±1.135)°,对照组为(-0.916±0.808)°;观察组左室跨壁扭转峰值为(-3.209±1.326)°,对照组为(-2.886±1.481)°.观察组左心室扭转角度均高于正常对照组,差异有显著性(P〈0.05)。结论妊娠期糖尿病母亲所生新生儿心脏的结构与功能受到不同程度的损害。超声二维斑点追踪技术是检测包括新生儿在内左心功能早期改变的良好手段。Objective To evaluate the effect of Gestational diabetes mellitus (GDM) on neonatal cardiac function and structure by two dimensional ultrasound speckle-tracking imaging (STI). Methods Two-dimensional active images of left ventricular at basal short-axis view and the thickness of left ventricular wall were acquired in 45 infants of gestational diabetes mellitus mothers and 45 normal neonates and left ventricular torsion was calculated by STI. Results The interventricular septal thickness of GDM group was (0.45 ± 0.06) cm, while that of the control group was (0.34 ± 0.05) cm, with significant difference (P〈0.05). The posterior left ven- tricular wall thickness of GDM group was (0.45 ± 0. 17) cm, while that of the control group was (0.31 ± 0.02) cm, with significant difference (P〈0.05). The peak endomembranal rotation of GDM group was (-4.713 ± 2.049)° , while that of the control group was (-3.744 ± 1.854)° ;the peak bulk rotation of GDM group was (-2.351 ± 1.429)° , while that of the control group was (-1.413 ± 0.918)° ; the peak membranal rotation of GDM group was (-1.457±1.135)° ,the control group was (-0.916 ± 0.808)° ;The peak mural torsion of GDM group was (-3.209± 1.326)° ,the control group was (-2.886 + 1.481)° .The left ventricular torsion in GDM group was higher than that of control group with significant difference (P〈0.05). Conclusion The Cardiac function and structure of infant of gestational diabetes mellitus mother are impaired. STI can exactly evaluate the characteristics of neonatal cardiac function.
关 键 词:超声二维斑点追踪技术 妊娠期糖尿病 新生儿心脏 左室扭转角度
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