不同肥胖程度阻塞性睡眠呼吸暂停低通气综合征患者的血浆神经肽Y水平研究进展  

Advance research of plasma NPY level in patients with obstructive sleep apnea hypopnoea syndrome of different obese degree

作　　者：王晓琼[1] 

机构地区：[1]安徽省蚌埠医学院第一附属医院呼吸科,230000

出　　处：《国际呼吸杂志》2013年第5期374-376,共3页International Journal of Respiration

摘　　要：阻塞性睡眠呼吸暂停低通气综合征以打鼾、睡眠结构紊乱、呼吸暂停和呼吸浅表、夜间反复低氧血症和高碳酸血症等为主要特征。肥胖是阻塞性睡眠呼吸暂停低通气综合征的主要风险。神经肽Y是一种由36个氨基酸残基组成的，与肥胖具有相关性的多肽。现对于不同肥胖程度阻塞性睡眠呼吸暂停低通气综合征患者的血浆神经肽Y水平研究进展进行文献综述。Obstructive sleep apnea hypopnea syndrome （OSAHS） is a disabling condition characterized by snoring, sleep architecture disorders, apnea and shallow breathing, repeated episodes of nocturnal hypoxemia and hypercapnia during night. Obesity is a major risk for OSAHS. Neuropetide Y （NPY） is a polypeptide with 36 amino acids, which is associated with obesity. Here we present the advance research of plasma NPY level in patients with OSAHS of different obese degree.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 神经肽Y 肥胖 

分 类 号：R766[医药卫生—耳鼻咽喉科]