胃癌患者胃大部切除术后感染的危险因素分析  

Risk factors for infections in gastric cancer patients after subtotal distal gastrectomy

作　　者：赵洁[1] 王晓丽[1] 罗文文[1] 王红敏[1] 贺孝文[2] 

机构地区：[1]绍兴市人民医院消化内科,浙江绍兴312000 [2]绍兴市人民医院胃肠外科,浙江绍兴312000

出　　处：《中华医院感染学杂志》2013年第7期1574-1576,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析医院胃癌患者行胃大部切除术后感染的相关影响因素,为术后感染的预防治疗提供参考依据。方法回顾性分析医院2007年1月-2011年10月普外科行胃大部切除术的胃癌患者临床资料190例,单因素分析其术后感染的危险因素。结果 190例行胃大部切除术的胃癌患者共发生感染32例,感染率为16.8%;术后感染以手术切口感染为主,占40.6%,其次为腹腔、呼吸道和肠道感染,分别占25.0%、21.9%和12.5%;单因素χ2检验显示,年龄>60岁、手术时间>100min,肿瘤临床分期差、术中输血、白细胞计数<2×109/L是胃癌患者胃大部切除术后感染的高危因素(P<0.05),而与患者的性别和手术方式无显著相关性。结论胃癌患者胃大部切除术后以手术切口感染为主,其次为腹腔和呼吸道感染,年龄、手术时间、临床分期、术中输血、白细胞计数是胃癌患者胃大部切除术后感染的高危因素。OBJECTIVE To investigate the risk factors of infections in gastric cancer patients after subtotal distal gastrectomy so as to provide the theoretical basis for prevention of the infections. METHODS A total of 190 cases of gastric cancer patients, who underwent the subtotal distal gastreetomy from Jan 2007 to Oct 2011, were retrospectively analyzed in the hospital. The univariate analysis of risk factors of the infections was performed. RESULTS Of totally 190 cases of gastric cancer patients investigated, 32 cases were infected with the infection rate of 16. 8%. The main postoperative infection site was surgical wound, accounting for 40. 6%, followed by abdominal cavity （25.0%）, respiratory tract （21.9%）, and intestinal tract （12.5%）. The ;x^2 analysis showed that more than 60 years of age, operation duration more than 100 rain, poor tumor stage, intraoperative blood transfusion, and white blood cell count less than 2 × 10^9/L were the high risk factors for the infections in the gastric cancer patients after subtotal distal gastrectomy（P〈0.05）, however, there was no significant correlation between the infections and the gender and surgical approach. CONCLUSION The surgical incision infection is dominant in the gastric cancer patients after subtotal distal gastrectomy, followed by abdominal cavity infection and respiratory tract infection. The age, operation duration, tumor stage, intraoperative blood transfusion, and white blood cell count are the high risk factors of infections in gastric cancer patients after subtotal distal gastrecto- my.

关 键 词：胃癌 胃大部切除术 术后感染 

分 类 号：R619.3[医药卫生—外科学]