地胆草属药用植物研究进展  

Studies on Medicinal Plants of Elephantopus(Compositae)

作　　者：王建军[1] 刘宇婧[1] 徐家星[1,2] 王敖[1] 王业玲[1] 龙春林[1,3] 

机构地区：[1]中央民族大学,北京100081 [2]云南农业大学 [3]中国科学院昆明植物研究所,昆明650201

出　　处：《天然产物研究与开发》2013年第3期401-409,415,共10页Natural Product Research and Development

基　　金：国家自然科学基金项目(31070288;31161140345);教育部和国家外专局高等学校学科创新引智计划项目(B08044);985工程项目(98502-006004;98506-01000101)

摘　　要：菊科地胆草属植物被广泛用于多个国家或地区的传统医药中,该属中的地胆草(Elephantopus scaber)具有清热、凉血、利湿的功效;我国多个民族也用来治疗感冒、肾炎、肝炎以及虫蛇咬伤等多种伤病。该属植物含有多种化学成分,按结构类型主要有倍半萜烯内酯、三萜、甾体、黄酮等化合物。现代药理研究证明该属药用植物粗提物及单体具有抗菌消炎、抗病毒、抗原虫以及抗肿瘤等多种生物活性。本文系统综述了该属药用植物传统知识、化学成分及生物活性的研究进展,可为该属植物的进一步开发利用提供参考。Plants in Elephantopus （Compositae） are widely used in traditional medicine in many countries or regions. El- ephantopus scaber is effective with functions of clearing heat, cooling blood and promoting dieresis. It is used to treat cold,nephritis, hepatitis,insect and snake bites, and so on by many different nationalities in China. Sesquiterpene laetone, triterpene,steroids and flavones have been isolated from this genus. The pharmacological research showed that the crude extract and monomeric Compounds are with various bioactivities, such as antibacteria, antiinflammation, antivirus, anti-protozoa and anti-tumor. This paper reviewed the research progress of plants in Elephantopus in terms of traditional knowledge,chemical compounds and bioactivities. It can provide references for the further development of plants in this genus.

关 键 词：地胆草属 传统知识 倍半萜烯内酯 抗肿瘤 利什曼原虫病防治 

分 类 号：R284.2[医药卫生—中药学]