广西乙脑发病季节的分布特点分析  

Analysis of seasonal distribution of epidemic encephalitis B in Guangxi

作　　者：梁能秀[1] 谭毅[2] 谢志春[1] 韦艳妮[1] 徐世民[1] 李春英[1] 莫丽华[1] 谢海[1] 

机构地区：[1]广西医科大学公共卫生学院流行病学教研室,广西南宁530021 [2]广西壮族自治区疾病预防控制中心病毒性传染病防制所

出　　处：《现代预防医学》2013年第8期1519-1520,1523,共3页Modern Preventive Medicine

基　　金：广西区卫生厅科研课题广西重要病毒性脑炎分子流行病学研究(Z2008204)

摘　　要：目的探讨开展乙脑疫苗预防接种前后乙脑发病的时间分布特征,以指导今后的防制工作。方法应用圆形分布方法对广西1960～2010年乙脑发病资料进行分析。结果乙脑疫苗预防接种前、疫苗推广期和计划免疫管理期,3个不同时期乙脑发病的平均角(α)分别为188.592°,181.88°和180.961°,高峰日分别为7月10日,7月3日和7月2日,高峰期分别为6月9日～8月10日,6月1日～8月5日,6月2日～8月1日,集中度r值由0.869逐渐减少至0.845,s值在计划免疫管理期最小,不同阶段发病高峰日的差异有统计学意义(P﹤0.01)。结论广西乙脑发病有严格的季节性;随着乙脑疫苗接种工作的开展,乙脑的发病率逐渐降低,发病的高峰日提前,高峰期缩短。OBJECTIVE To understand the regulation of time distribution of epidemic encepbalitis B in Guangxi, and explore the characteristic of time distribution before and after immunization of the disease, which will provide scientific evidence for control and prevention METHODS Data on encephalitis B from 1960 to 2010 in Guangxi were analyzed with circular distribution method. RESULTS The average angle of JE incidence of three different stages were 188.592°, 181.880° and 180.961°, respectively; The average peak day of the disease were on the 10° July, the 3° July and the 2th July, respectively; The duration of the peak were from the 9th June to the 10th August, from the 1st June to the 5th August and from the 2nd June to the 1st August, respectively. R value which indicated the morbidity of the disease gradually reduced from 0.869 to 0.845 before initial and routine immunization, in immunization management periods. The value indicating the mobidity of the disease dispersion was 29.60, which was the least value of s value, there was difference among the peak day at different stages （P 〈 0.01 ）. CONCLUSION There is a seasonal characteristic of the prevalence of the disease, the morbidity is gradually reduced, the peak day had been moved up and the peak stage is shortened along with the implementation of encepbalitis B immunization.

关 键 词：圆形分布 乙型脑炎 时间分布 疫苗接种 

分 类 号：R512.32[医药卫生—内科学]