凉山州2006～2011年吸毒哨点人群HIV-1新发感染研究  

Study on the recent HIV-1 infection in sentinel IDU group of Liangshan state from 2006 to 2011 by BED-CEIA

作　　者：马志凌[1,2] 马名驹[2] 卫大英[2] 边仕超[2] 马兆瑾[2] 刘茜[2] 廖强[2] 梁姝[3] 于海英[4] 裴晓方[1] 

机构地区：[1]四川大学华西公共卫生学院(华西第四医院),四川成都610041 [2]凉山州疾病预防控制中心 [3]四川省疾病预防控制中心 [4]中国疾病预防控制中心

出　　处：《现代预防医学》2013年第8期1528-1530,共3页Modern Preventive Medicine

摘　　要：目的了解2006～2011年凉山州吸毒哨点人群中HIV-1新发感染情况。方法对2006、2008、2009、2010、2011年在吸毒哨点人群中采集的4103份有效样本,进行HIV检测,初筛阳性的样本经免疫印迹法(WB)证实后,进行BED检测,评估HIV-1的新发感染率。结果通过对4103份样本的检测,发现2006、2008、2009、2010、2011年的HIV-1感染率和新发感染率分别为:22.4%和6.89%、29.6%和8.92%、26.2%和13.22%、21.5%和8.05%、23.4%和10.12%。结论 2006～2011年,凉山州吸毒人群HIV-1感染率居高不下,而且新发感染率有上升趋势,提示凉山州吸毒人群艾滋病流行形势严峻,需加大防控力度。OBJECTIVE To investigate the HIV-1 recent infection status among injection drug user （IDU） in Liangshan state from 2006 to 2011. METHODS The 4103 valid samples were collected from IDU in 2006, 2008, 2009, 2010 and 2011 for HIV screen. The positive samples from the screening test were confirmed with Western blotting. The confirmed samples were further tested by BED-CEIA to evaluate the rate of recent infection. RESULTS After the test for 4103 samples, the results demonstrated that the infection rateand recent infection rate from 2006 to 2011 in Liangshan sentinel IDU group were 22.4% and 6.89%, 29.6% and 8.92%, 26.2% and 13.22%, 21.5% and 8.05%, 23.4% and 10.12%, respectively. CONCLUSION After 5 years survey in Liangshan sentinel IDU group, the results demonstrate that the HIV-1 infection rate of them is still high and further more a higher recent infection rate by BED-CEIA is noticed. This implies that the HIV epidemic in Liangshan is still severe and more preventive measures should be needed.

关 键 词：BED—CEIA HIV 新发感染 

分 类 号：R512.91[医药卫生—内科学]