非淋球菌性尿道炎患者支原体和衣原体感染的流行病学调查  

Epidemic Investigation of Chlamydia Trachomatis and Mycoplasma Hominis Infections in Nongonococal Urethritis

作　　者：张钧[1] 管茶英[1] 谢鑫友 詹定凤[1] 

机构地区：[1]浙江大学医学院附属邵逸夫医院检验科,310016

出　　处：《浙江临床医学》2000年第8期509-510,共2页Zhejiang Clinical Medical Journal

摘　　要：目的为了解沙眼衣原体、人型支原体、解脲支原体感染所致非淋球菌性尿道炎 (NGU)的流行状况和分布特征。方法对246例 (男142例 ,女102例 )NGU患者 ,用斑点酶免疫渗滤法检测泌尿生殖道标本的沙眼衣原体抗原 ;用肉汤培养法检测人型支原体、解脲支原体 ,同时做解脲支原体的药敏。结果衣原体阳性47例 (19.1 % ) ,人型支原体阳性13例 ,解脲支原体阳性81例 ,同一标本检出两种支原体11例。支原体感染率在不同性别中有显著差异 (p<0.01) ;衣原体感染率在不同性别中无明显差异。解脲支原体的药敏提示对强力霉素、四环素、原始霉素、交沙霉素高度敏感 ,敏感率均>90 %。结论临床考虑NGU应同时检测解脲支原体和沙眼衣原体。强力霉素和四环霉素可作疑似GNU的经验用药。Objective To explore the epidemics and distribution of nongonococal urethritis (NGU). Methods Chlamydia trachomatis was examined by Dot immunoenzyme filtration assay and mycoplasma hominis and ureaplasma urealyticum were examined by culturing the urogenital secretions. The drug sensitivity of ureaplasma urealyticum was also carried out. Results 47 cases (19.1%) revealed positive ureaplasma urealyticum, 83 cases (33.7%) was mycoplasma hominis positive. Significant difference of ureaplasma urealyticum infection rate was observed between men and women patients (P<0.01) while the difference in Chlamydia trachomatis infection was not observed between the men and women cases. Conclusion Ureaplasma urealyticum was sensitive to the treatment of doxycycline, tetracycline, pristinamycin and josamycine.

关 键 词：非淋球菌性 尿道炎 沙眼衣原体 解脲支原体 

分 类 号：R695[医药卫生—泌尿科学]