地佐辛与瑞芬太尼在无痛人流术麻醉的应用比较  

Comparison of the analgesic effect of dezocine and remifentanil for artificial abortion

作　　者：潘华[1] 王海丽[1] 屈海波[1] 

机构地区：[1]河南省三门峡市中心医院,472000

出　　处：《中国医疗前沿》2013年第5期61-62,共2页China Healthcare Innovation

摘　　要：目的评价地佐辛与瑞芬太尼用于人流术的麻醉效果。方法 120例行人流术的患者分为两组,D组静脉注射地佐辛;R组静脉瑞芬太尼,1min后以持续泵注。随后静注异丙酚。记录麻醉开始诱导前(T0)、意识消失时(T1)、扩宫颈时(T2)及术毕苏醒时(T3)的MAP、SpO2、HR;记录苏醒时间及异丙酚总用量;记录不良反应发生率及患者清醒后5min、10min、20min及离院时的VAS评分。结果 T1、T2、T3时点MAP、HR较T0低(P<0.05);T1、T2时点SPO2较T0低(P<0.05)。D组患者不良反应的发生率低于R组(P<0.05)。10min、20min、离院时VAS评分D组低于R组(P<0.05)。结论地佐辛复合异丙酚用于人流术镇痛效果确切,值得推广。Objective To investigate the analgesic effect of dezocine and remifentanil for artificial abortion.Methods One hundred and twenty patients who suffered from artificial abortion in our hospital were randomly divided into two groups： group D and group R.Group D was treated with dezocine combined with propofol,and group R was treated with propofol and remifentanil.The MAP,SPO2 and HR were recorded at before induction of anesthesia（T0）,lost consciousness（T1）,beginning of cervical dilatation（T2）,awaking from anesthesia（T3）.The time of recovery and the total dosage of propofol,and the incidence adverse reactions were also recorded.The visual simulation scores（VAS） were also recorded and analyzed at the time point of 5,10,20 min after recovery from anesthesia and leave the hospital.Results The MAP and HR at T1,T2,T3 were lower than that at T0 in two groups.The SpO2 at T1 and T2 was lower than T0.The incidence of respiratory depression,dizziness cough,postoperative nausea and vomiting in group D was lower than in group R.The VAS score at the time point of 10,20min and leave the hospital in group D was lower than in group R.Conclusion Dezocine combined with propofol for artificial abortion has the advantage exact postoperative analgesia and can be safely and effectively used for artificial abortion.

关 键 词：地佐辛 瑞芬太尼 人工流产术 镇痛 

分 类 号：R719.3[医药卫生—妇产科学]