过敏性鼻炎-哮喘综合征治疗方法的成本效果分析  

The Cost-effectiveness analysis of the treatment of allergic rhinitis-asthma syndrome

作　　者：蓝金全 肖克安 孙渝生[1] 刘佩沂 

机构地区：[1]广东省中山市黄圃人民医院,广东中山528429

出　　处：《吉林医学》2013年第9期1619-1620,共2页Jilin Medical Journal

摘　　要：目的:探讨过敏性鼻炎-哮喘综合征治疗方法的成本效果,从而选择合理的治疗药物。方法:过敏性鼻炎-哮喘综合征患者200例根据药物应用的不同分为糖皮质激素组(A组)、抗组胺组(B组)、白三烯受体拮抗剂组(C组)、抗-IgE单克隆抗体组(D组)和转移因子组(E组),分别应用相应的药物治疗。结果:D组与E组的有效率都高于A组、B组、C组(P<0.05),D组与E组的成本明显高于A组、B组、C组(P<0.05),A组与C组的C/E值明显少于其他三组(P<0.05),进行敏感度分析,表明影响因素在一定的变化范围内并不影响结果。结论:糖皮质激素法与白三烯受体拮抗剂法是治疗过敏性鼻炎-哮喘综合征的最佳治疗方法,值得推广应用。Objective To investigate the cost-effectiveness of allergic rhinitis-asthma syndrome treatment for reasonable choice of treatment drugs.Methods 200 cases of allergic rhinitis-asthma syndrome patients were equally divided into glucocorticoid group（A）,the anti histamine group（B）,leukotriene receptor antagonist group（C group）,anti-IgE monoclonal antibody group（D） and transfer factor group（E） depending on the drug application respectively,there were appled the appropriate medication.Results Group D and E efficiency were higher than A,B,C group（P 0.05）,D group and E group cost were significantly higher than the A,B,C group（P〈0.05）,group A and group C C/E values significantly were less than the other three groups（P〈0.05）,sensitivity analysis showed that the influencing factors can not affect the results.Conclusion The glucocorticoid law and leukotriene receptor antagonists are the best treatment for the treatment of allergic rhinitis-asthma syndrome,should be widely applied.

关 键 词：过敏性鼻炎-哮喘综合征 成本效果 糖皮质激素 白三烯受体拮抗剂 

分 类 号：R765.21[医药卫生—耳鼻咽喉科] R562.25[医药卫生—临床医学]