中西医结合治疗小细胞肺癌临床研究  

Observation on the Curative Effect of Integration of Traditional Chinese Medicine and Western Medicine for the Treatment of Small-Cell Lung Cancer

作　　者：张春盈[1] 孙淑君[1] 刘英杰[1] 李俊[1] 杨新华[1] 

机构地区：[1]中国人民解放军第152中心医院,河南平顶山467000

出　　处：《中医学报》2013年第4期481-482,共2页Acta Chinese Medicine

摘　　要：目的:观察中西医结合治疗小细胞肺癌的临床疗效。方法:将80例小细胞肺癌患者随机分为两组,对照组采用规范的EP方案化疗,治疗组在对照组基础上气阴两虚证加用生脉饮或百合固金汤加减治疗;气滞血瘀证加用血府逐瘀汤加减治疗;脾肾阳虚证加用大补元煎加减治疗。治疗4～6个周期后按WHO标准评价治疗效果及不良反应。结果:治疗组有效率为67.4%,对照组有效率为32.5%,治疗组明显高于对照组,两组比较差异显著(P<0.05);并且治疗组患者骨髓不良反应及消化系统不良反应均明显低于对照组(P<0.01)。结论:中西医结合治疗小细胞肺癌较单纯化疗临床疗效好,不良反应少。Objective：To observe the curative effect of using integration of traditional Chinese medicine and western medicine for tne treatment of small-cell lung cancer.Methods：80 patients of small-cell lung cancer were randomly divided into the two groups.The control group was given intravenous chemotherapy with standard EP option.For the treatment group,on the basis of intravenous chemotherapy,qi and yin deficiency syndrome was additionally given modified Shengmai Drink or Baihe Gujin Decoction;stagnation of qi and blood syndrome was additionally treated with addition or subtraction Xuefu Zhuyu Decoction;yang deficiency of spleen and kidney was added Major Original-Qi Tonifying Decoction for treatment.Treatment effects and adverse reactions were evaluated according to WHO standard after four to six weeks of treatment.Results：The effective rate of the treatment group was 67.4% while the rate of the control group 32.5%.The treatment group was superior to the control group,and comparions between them showed that the differences were significant（P0.05）.Adverse reactions of bone marrow and the digestive system in the treatment group were significantly lower than that in the control group（P0.01）.Conclusion：The curative effect of using integration of traditional Chinese medicine and western medicine for tne treatment of small-cell lung cancer is better than the pure chemotherapy,and adverse reaction is low.

关 键 词：小细胞肺癌 辨证论治 化疗 生脉饮 百合固金汤 血府逐瘀汤 大补元煎 

分 类 号：R273[医药卫生—中西医结合]