碳氮双键异构化在荧光传感机制中的应用  

APPLICATION OF DOUBLE-BONDED CARBONIC ACID ISOMERIZATION IN A NEW EMERGING FLUORESCENT SIGNALING MECHANISM

作　　者：韩燕[1] 郝迷花[1] 

机构地区：[1]新乡学院化学与化工学院,河南新乡453003

出　　处：《精细石油化工》2013年第2期68-72,共5页Speciality Petrochemicals

摘　　要：C=N异构化作为一种新型的传感机制,自2007年被报道以来,已经被广泛应用于荧光化学传感器分子的设计之中,并表现出良好的传感性能。对于含有C=N双键的化合物分子,C=N的异构化会加剧分子的激发态的非辐射跃迁,从而使得其荧光淬灭。当其与特定的客体分子相互作用时,C=N的异构化会受到抑制,使得分子的荧光恢复,从而实现对这种客体分子的检测。综述了C=N异构化这种新型的荧光传感机制的研究进展,包括这种传感机制的基本原理,其在阴、阳离子及中性分子检测中的应用,并展望了该领域的发展趋势。As a new emerging signaling mechanism, C=N isomerization has been widely utilized in the design of novel fluorescent chemosensors with well performance since it was reported in 2007. It is found that compounds containing unbridged C=Nbonds were usually non-fluorescent as C=N isom- erization was the predominant decay process of excited states. However, compounds con＊aining a cy- clic C=N bond or complexing with a guest species to restrict the rotation of C=N bond would be strongly fluorescent. Then, it is expected that luminescence turn-on sensors toward specific analytes can be sophisticatedly designed by virtue of the suppression of C=N isomerization. Research progres- ses including basic principle of sensing mechanisms and application in the detection of cations, anions as well as neutral molecular are stated. The trend is looked ahead as well.

关 键 词：荧光传感器 碳氮双键异构化 锌离子 镉离子 镁离子 次氯酸根 半胱氨酸 同型半胱氨酸 亚硫酸氢根 

分 类 号：O622.4[理学—有机化学] O657.38[理学—化学]