On-chip fast mixing by a rotary peristaltic micropump with a single structural layer  

作　　者：DU Min MA ZengShuai YE XiongYing ZHOU ZhaoYing 

机构地区：[1]State Key Laboratory of Precision Measurement Technology and Instruments,Department of Precision Instruments and Mechanology,Tsinghua University

出　　处：《Science China(Technological Sciences)》2013年第4期1047-1054,共8页中国科学（技术科学英文版）

基　　金：supported by the Major State Basic Research Development Program of China ((Grant No. 2007CB310504);the National Natural Science Foundation of China (Grant No. 50730009)

摘　　要：In this work,a rotary pump based micromixer for on-chip rapid mixing and liquid transportation is demonstrated and characterized.Both pumping and mixing are realized using a microfluidic chip with a single structural polydimethylsiloxane layer and a portable electric control system.The rotary pump consists of an annular channel and is driven by a motor and magnets.The flow field caused by the peristaltic movement of the channel membrane of the rotary pump is simulated and analyzed.By statistically calculating and comparing the normalized standard deviations of the flow velocity components in a microchannel,it is revealed that up-and-down mixing is the fastest,followed by segment mixing and parallel mixing.Two mixing styles,segment mixing and parallel mixing,were experimentally demonstrated using the chip.The pump achieved 90% of the mixing index in 1 s for the segment mixing type.As for the parallel mixing type,the mixing index was up to 90% after 5 s,which is more than 100-fold improvement compared to conventional mixing by interfacial diffusion.The mixing speeds in both directions were improved prominently by increasing the rotational speed of the pump.

关 键 词：microfluidic MIXING rotary pump magnetic driving 

分 类 号：TH314[机械工程—机械制造及自动化]