喉罩通气全凭吸入七氟醚麻醉在乳腺癌根治术中的应用研究  

Application study of laryngeal mask airway dependent on sevoflurane inhalation anesthesia in radical mastectomy

作　　者：李英娜[1] 刘志建[2] 侴伟平[1] 

机构地区：[1]辽宁省肿瘤医院麻醉科,辽宁沈阳110042 [2]沈阳市儿童医院耳鼻喉科,辽宁沈阳110032

出　　处：《中国医药导报》2013年第8期90-92,共3页China Medical Herald

摘　　要：目的研究喉罩通气全凭吸入七氟醚麻醉在乳腺癌根治术中的应用。方法以2009年5月～2012年6月于辽宁省肿瘤医院住院的63例乳腺癌根治术患者为研究对象,分为观察组32例和对照组31例。观察组采用七氟醚进行诱导,待成功置入喉罩后采用单纯七氟醚吸入进行麻醉维持;对照组采用传统静脉注射麻醉诱导,待成功置入喉罩后,采用持续吸入七氟醚及间断注射顺苯磺酸阿曲库铵麻醉维持。监测两组患者麻醉情况。结果观察组喉罩拔除时间明显短于对照组,差异有统计学意义(P<0.05)。两组患者置入喉罩时(T2)平均动脉压(MAP)较麻醉诱导开始时(T1)明显降低,差异有统计学意义(P<0.05);在T2时对照组MAP较观察组更低,差异有统计学意义(P<0.05);对照组T2时心率(HR)较T1时明显较慢,差异有统计学意义(P<0.05);各时间点两组间血氧饱和度比较,差异无统计学意义(P>0.05)。结论喉罩通气全凭吸入七氟醚麻醉在乳腺癌改良根治术中是一种安全、有效、值得临床推广应用的麻醉方法。Objective To study the application of laryngeal mask airway dependent on sevoflurane inhalation anesthesia in patients underwent radical mastectomy.Methods 63 patients underwent elective modified radical mastectomy in tumor hospital of Liaoning Provirce from May 2009 to June 2012 were studied,and divided into observation group with 32 cases and control group with 31 cases.Patients in the observation group were inducted with Sevoflurane,and laryngeal mask successfully implanted,maintained by sevoflurane anesthesia alone.Patients in the control group were anesthesiaed with traditional intravenous induction,and laryngeal mask successfully implanted,maintained by continuous inhalation of sevoflurane and intermittent injection with benzenesulfonate atracurium.The information of anesthesia were studied.Results The time unplug the laryngeal mask in the observation group was significantly shorter than that in the control group,there was statistically significant（P 0.05）.Mean arterial blood pressure（MAP） values in T 2 time point in the two groups were significantly lower than that in T 1,the differences were significant（P 0.05）.MAP in the T 2 time point in the control group was lower than that in observation group,the difference was significant（P 0.05）. The HR in the T 2 time point in the control group was significantly slower than the T 1 time point,the difference was significant（P 0.05）.Oxygen saturation values in each time point between the two groups had no significant differences. Conclusion The laryngeal mask airway dependent on sevoflurane inhalation anesthesia in modified radical mastectomy is a safe,effective and worthy of clinical application method.

关 键 词：喉罩通气 七氟醚 乳腺癌根治术 

分 类 号：R614[医药卫生—麻醉学]