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作 者:高杰[1] 张艳君[1] 冯丽芳[1] 梁锡铭[1] 侯惠如[1]
出 处:《中国医药导报》2013年第8期139-140,142,共3页China Medical Herald
基 金:解放军总医院科技创新苗圃基金项目(编号:11KMM54)
摘 要:目的观察应用复方醋酸地塞米松乳膏外涂加纱布固定与美皮康两种换药方法对老年患者中心静脉置管处周围皮肤过敏的治疗效果。方法将我院38例中心静脉置管处局部皮肤过敏患者按发生的先后分为地塞米松组和美皮康组,每组各19例。地塞米松组采取常规复合碘局部消毒后用复方醋酸地塞米松乳膏外涂加纱布固定;美皮康组在常规复合碘局部消毒后用美皮康固定。结果地塞米松组治愈5例(26.3%),缓解14例(73.7%),总有效率为100.0%,无无效病例。美皮康组治愈17例(89.5%),缓解1例(5.3%),总有效率为94.7%,无效1例(5.3%)。两组总有效率比较差异无统计学意义(P>0.05),但美皮康组的治愈率明显优于对照组(P<0.05)。结论复方醋酸地塞米松乳膏对皮肤过敏的有效率高,但起效时间较长;美皮康的治愈率显著且简便易行,但有过敏现象发生,且价格昂贵,需掌握应用对象和应用时机。Objective To observe the treatment effect of the Compound Dexamethasone Acetate Cream coating combined with gauze fixation and the Meipikang method for the skin allergy in the central venous catheterization area in elderly patients.Methods 38 patients with skin allergy in the central venous catheterization area were divided into the Dexamethasone group and the Meipikang group with 19 patients in each group according to the occurrence time.The Dexamethasone group was given Dexamethasone acetate cream coating and gauze fixation after the local disinfection using conventional compound iodine.The Meipikang group was given Meipikang fixation after the local disinfection using conventional compound iodine.Results In the Dexamethasone group,5 patients(26.3%) were cured,14 patients(73.7%) relieved and none was ineffective,with the total effective rate of 100.0%.In the Meipikang group,17 patients(89.5%) were cured,1 patient(5.3%) relieved and 1 patient was ineffective,with the total effective rate of 94.7%.The effective rates of the two groups were not significantly different(P 0.05),but the cure rate of the Meipikang group was significantly superior to that of the control group(P 0.05).Conclusion Compound Dexamethasone Acetate Cream is highly effective for skin allergy,but its onset time is long.Meipikang has a significant cure rate and is simple and convenient,but it has allergic reaction and is expensive,thus the application object and application timing should be mastered.
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