肾功能衰竭伴充血性心力衰竭老年患者血液循环力学临床研究  被引量:4

Clinical research of blood circulation mechanics in renal failure elderly patients with congestive heart failure(CHF)

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作  者:刘波[1] 施向东[1] 

机构地区:[1]浙江省湖州市中心医院肾内科,浙江湖州313000

出  处:《中国现代医生》2013年第6期23-25,共3页China Modern Doctor

基  金:浙江省科技计划项目

摘  要:目的探讨肾功能衰竭伴充血性心力衰竭(CHF)老年患者血液循环力学的变化规律。方法选择210例肾功能衰竭伴充血性心力衰竭患者,其中老年患者组(A组)与中年患者组(B组)各105例,对其血液循环力学,心脏泵血功能等进行检测和数据统计。结果 CVP[(27.3±10.2)cm H2O与(24.1±10.8)cm H2O,t=2.435,P=0.020]、ECV[(4371±1338)mL与(3112±1020)mL,t=7.597,P=0.000]、SV[(168±49)mL与(115±43)mL,t=7.798,P=0.000]、CO[(14.3±3.8)L/min与(12.1±4.0)L/min,t=4.768,P=0.000]、LDV[(385±151)mL与(260±89)mL,t=7.854,P=0.000]、LSV[(224±95)mL与(136±60)mL,t=7.201,P=0.000],A组均高于B组。EP[(177±30)mm Hg与(182±25)mm Hg,t=2.314,P=0.013]、心肌负变力系数[(0.612±0.150)与(0.691±0.191),t=3.120,P=0.001]、射血分数[(0.431±0.032)与(0.442±0.034),t=2.501,P=0.020]、舒张压[(88±15)mm Hg与(110±20)mm Hg,t=8.221,P=0.000]、系统总阻抗[(950±211)gcm-1s-1与(1215±298)gcm-1s-1,t=7.098,P=0.000]、SBP[(163±24)mm Hg与(174±21)mm Hg,t=3.513,P=0.001],A组均低于B组。DBP(χ2=16.501,P=0.000,OR=0.761,95%CI:0.712~0.795)、收缩压(χ2=12.034,P=0.000,OR=1.152,95%CI:1.090~1.210)、射血阻力(χ2=17.901,P=0.000,OR=0.702,95%CI:0.860~0.955)、中心静脉压(χ2=14.598,P=0.000,OR=0.761,95%CI:0.661~0.735)、左室舒张末期容量(χ2=21.104,P=0.000,OR=0.953,95%CI:0.890~0.990),均是引发老年肾功能衰竭患者并发充血性心力衰竭的高危因子。结论肾功能衰竭伴充血性心力衰竭老年患者的容量负荷增加,心肌收缩功能和心脏压力负荷下降。Objective To investigate the renal failure with congestive heart failure elderly patients and their blood circulation mechanics change rule. Methods A total of 210 patients with renal failure and congestive heart failure patients, who were divided into the elderly group (group A) and middle-aged patients group (group B), and tested the 105 cases of the blood circulation mechanics, heart pump function and data statistics. Results The CVP (27.3±10.2 ) cmH20 vs (24.1±10.8 cmH20, t = 2.435, P = 0.020, ECV (4371±1338) mL vs (3112±1020) mL, t = 7.597, P = 0.000, SV (168±49) mL vs (115±43) mL, t = 7.798, P= 0.000, CO (14.3±3.8 L/min vs (12.1±4.0)L/rain, t = 4.768, P= 0.000, LDV (385 ±151) mE vs (260 ±89) mE, t = 7.854, P = 0.000, LSV (224 ± 95) mL vs (136 ± 60) mL, t = 7.201, P = 0.000.A group's data was higher than group B's. The EP (177±30) mm Hg vs (182±25) mm Hg, t = 2.314, P= 0.013. myocardial negative inotropic coefficient 0.612±0.150) vs (0.691±0.191), t = 3.120, v = 0.00 0jeetion fraction (0.431± 0.032) vs (0.442+0.034), t = 2.501, P = 0.020, diastolic pressure (88+15) mmHg vs (110+and) mm Hg, t = 8.221, P = 0.000, the system total impedance (950±211) gem^-1s^-1 vs (1215+298)gem^-1s^-1, t = 7.098, P = 0.000. SBP (163±24) mm Hg vs (174± 21) mm Hg, t = 3.513, P = 0.001. DBP 2 = 16.501, P = 0.000, OR = 0.761, 95% CI: 0.712 ± 0.795), systolic blood pressure (X2 = 12.034, P = 0.000, OR = 1.152, 95% CI: 1.090-1.210), ejection resistance (x^2 = 17.901, P = 0.000, OR = 0.702, 95% CI: 0.860-0.955), central venous pressure (X2 = 14.598, P = 0.000, OR = 0.761, 95% CI: 0.661-0.735), left ventricular end--diastolic olume (X2= 21.104, P= 0.000, OR = 0.953, 95% CI 0.890-0.990), all were the high risk factors with renal failure. Conclusion lderly patients with renal failure and congestive heart failure,who are with capacity load increases,and myoeardial systolic function

关 键 词:肾功能 充血性心力衰竭 力学 

分 类 号:R587.2[医药卫生—内分泌]

 

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