基底动脉粥样硬化斑块分布与脑梗死灶相关性的高分辨磁共振成像研究  

High-resolution MRI study on correlation of basilar artery atherosclerotic plaque distribution with brain infarction

作　　者：刘丹青[1] 蔡剑鸣[1] 马林[1] 蔡幼铨[1] 曹向宇[1] 王庆军[2] 韩旭[1] 

机构地区：[1]解放军总医院放射科,北京100853 [2]海军总医院医学影像科,北京100037

出　　处：《中国医学装备》2013年第4期21-24,共4页China Medical Equipment

基　　金：全军十二五科研计划面上项目(CWS11J065)"军队高血压患者ACE基因多态性与颈动脉斑块稳定状态的相关性研究"

摘　　要：目的:通过3.0T高分辨磁共振成像(HR-MRI)初步探讨基底动脉粥样硬化斑块的轴位分布特点及其与脑梗死灶的相关性。方法:对20例症状性基底动脉粥样硬化患者行DSA、颅脑MRI及基底动脉高分辨MRI检查。根据DSA对所有患者的基底动脉管腔狭窄程度进行分组,颅脑MRI对脑内的缺血软化灶进行统计。统计基底动脉管腔最狭窄的层面斑块在4个90o扇形角的分布情况。分析不同基底动脉管腔狭窄程度的斑块分布特点,评价椎基底动脉供血区存在缺血病变的斑块分布。结果:轻度及中度基底动脉管腔狭窄的患者有12例,斑块分布以左侧和腹侧者为主,而重度管腔狭窄者有8例,斑块分布差异不明显。椎基底动脉供血区MRI异常的患者有9例,斑块出现在腹侧最多。结论:轻度及中度管腔狭窄的基底动脉粥样硬化斑块分布以左侧和腹侧为主;椎基底动脉供血区存在缺血梗死灶者的基底动脉斑块较多分布在腹侧。[Abstract] Objective： To investigate the distribution of basilar artery atherosclerotic plaque and its relation to brain infarction using 3.0 T high-resolution magnetic resonance imaging（HR- MRI）. Methods： Twenty symptomatic patients with basilar artery atherosclerosis underwent DSA, cerebral MRI and HR-MRI of basilar artery scanning. The patients were subgrouped as mild, moderate and severe stenosis based on DSA. The lesions in the brain were recorded from MRI appearances. Axially, the narrowest lumen of basilar artery was divided into four 90°angle （right, ventral, left and dorsal）, and in the same slice the plaque distribution in every fan angle was added up. The plaque distribution of patients with different lumen stenosis of basilar artery was analyzed and its relationship with brain infraction was evaluated. Results： In 12 patients with mild or moderate lumen stenosis of basilar artery, the plaques were mainly distributed in the left and ventral sites. The plaques have no such distribution discrepancy for other 8 patients with severe lumen stenosis. There were 9 patients with abnormity in the territory of vertebrobasilar artery showed in cerebral MRI, and the plaques located mostly in the ventral site and least in the dorsal site. Conclusion： Basilar artery atherosclerotic plaques with mild or moderate lumen stenosis are mainly distributed in the left and ventral sites. Basilar artery atherosclerotic plaques with ischemic lesion in the territory of vertebrobasilar artery locate mostly in the ventral site and least in the dorsal site. [Key words] Basilar artery; Plaque; Distribution; Magnetic resonance imaging; Brain infarction

关 键 词：动脉粥样硬化斑块 硬化斑块分布 颅脑MRI 磁共振成像 基底动脉 高分辨 梗死灶 相关性 

分 类 号：R445.2[医药卫生—影像医学与核医学]