脱敏治疗对鼻内镜鼻窦手术预后影响的研究  

Study on Influence of Desensitization Therapy on Prognosis of Patients with Endoscopic Sinus Operation

作　　者：冯锡坚[1] 吕洁文[1] 麦周生[1] 

机构地区：[1]广东省东莞市厚街医院耳鼻咽喉科,523945

出　　处：《中华全科医学》2013年第4期551-551,581,共2页Chinese Journal of General Practice

基　　金：广东省东莞市科技局项目(2010105150080)

摘　　要：目的探讨脱敏治疗对鼻内镜鼻窦手术预后的影响。方法选取2010年5月-2011年7月于东莞市厚街医院采用鼻内镜鼻窦手术进行治疗的60例患者为研究对象,其中进行术前脱敏治疗30例患者为观察组,未进行术前脱敏治疗的30例患者为对照组,后将两组患者的治疗总有效率、复发率、治疗前后的血清特异性IgG4、EGF及ECP水平进行比较。结果观察组的治疗总有效率高于对照组,复发率低于对照组,治疗后的血清特异性IgG4水平均高于对照组,而血清EGF及ECP水平均低于对照组,P均<0.05。结论脱敏治疗可有效改善鼻内镜鼻窦手术患者的预后。Objective To study the influence of desensitization therapy on the prognosis of patients with endoscopic sinus operation.Methods Total 60 patients with endoscopic sinus operation in our hospital from May 2010 to July 2011 were selected as research object,and 30 patients who were treated with desensitization therapy before the operation were as the observation group,other 30 cases who were not with desensitization therapy before the operation were as the control group,then the total effective rate,recurrence rate and serum specific IgG4,EGF,ECP before and after the treatment two groups were compared.Results The total effective rate of observation group was higher than that of control group,recurrence rate was lower than that of control group,serum specific IgG4 after the treatment were all higher than those of control group,serum EGF and ECP were all lower than those of control group,all P0.05.Conclusion The desensitization therapy can effectively improve the prognosis of patients with nasal endoscopic sinus operation.

关 键 词：脱敏治疗 鼻内镜鼻窦手术 预后 

分 类 号：R765.213[医药卫生—耳鼻咽喉科] R765.41[医药卫生—临床医学]