曲安奈德注射液（确炎舒松A）局部注射在儿童瘢痕应用的疗效评价  

作　　者：何悦[1] 邱林[1] 

机构地区：[1]重庆医科大学附属儿童医院烧伤整形科,重庆400014

出　　处：《医学美学美容（中旬刊）》2013年第3期24-25,28,共3页

摘　　要：目的探讨肾上腺糖皮质激素--曲安奈德注射液（确炎舒松A）局部注射对小儿增生性瘢痕、疲痕疙瘩的治疗及预防瘢痕形成的疗效及安全性。方法对增生性瘢痕、瘢痕疙瘩及预防性瘢痕注射治疗的56例患儿，进行局部注射曲安奈德注射液，观察临床效果并进行回顾性分析、评价、总结。结果增生性瘢痕治疗效果好，有效率100％。瘢痕疙瘩直接注射效果较差，手术切除后联合注射治疗效果良好。术后预防性注射治疗，无增生性瘢痕发生。注射期间3例出现局部脂肪组织萎缩，除疼痛外，无其他不良反应发生。结论局部分次注射小剂量曲安奈德预防瘢痕形成和治疗瘢痕的效果良好，在儿童使用中具有安全性。Objective To investigate the clinical therapeutic and preventive efficacy on hypertrophic scar, keloid in children by intralcsional injecting .with glucocorticoid （Triamcinolone acetonide acetate）. Methods 36 children with hypertrophic scar and keloid were intralesional injected with Triamcinolone acetonide acetate, analyzed retrospectively, evaluated and summarized. Results Hypertrophic scar by intralesional injecting got good efficacy, effective rate was 100%. The efficacy of only intralesional injection on Keloid was Door, but excison combined with postoperative intralesional injection was obviously improved. 3cases appeared local fatty atrophy, and no other serious complications were observed except pain. Conclusion Among the various treatments and prevention for hypertrophic scar and keloid, intralesional injection ,with small dose Triamcinolone acetonide acetate was safety and efficacy in pediatric population.

关 键 词：曲安奈德注射液 儿童 局部注射 瘢痕 

分 类 号：R917[医药卫生—药物分析学]