组织多普勒成像对妊娠糖尿病孕妇及胎儿心脏功能的研究  

Evaluating cardiac function of pregnant women with gestational diabetes and fetuses by tissue Doppler imaging

作　　者：吴玮 余杨 李瑛 丁琳灵 彭波 蒋明 刘惠莲 秦岚 

机构地区：[1]深圳市第七人民医院超声室,广东深圳518081

出　　处：《海南医学》2013年第7期991-994,共4页Hainan Medical Journal

基　　金：2011年深圳市盐田区产业发展资金项目(编号:201102)

摘　　要：目的应用组织多普勒成像技术(DTI)检测妊娠糖尿病(GDM)孕妇与胎儿心脏功能状况,明确两者间的相互作用,为临床处置提供必要依据。方法对50例糖尿病组和50例正常对照组的孕妇及胎儿分别进行常规心脏参数及房室瓣环平面四个位点的心肌运动速度的检测,了解其心脏功能状况,并分别进行统计学处理。结果糖尿病组孕妇及胎儿心肌厚度明显大于对照组(P<0.05),心肌厚度增加在妊娠晚期(>33周)表现更为明显;糖尿病组胎儿较对照组胎儿Sm、Em及Am均下降,其差异具有统计学意义(P<0.05);而射血分数EF值均大于对照组(P<0.05)。糖尿病组孕妇房室瓣环心肌运动速度Sm、Em均降低,Am升高与对照组相比,差异均具有统计学意义(P<0.05),其舒张功能Em值的降低与胎儿Em值降低呈正相关(r=0.79,P<0.05),Am值的升高与胎儿Am值升高呈正相关(r=0.77,P<0.05)。结论组织多普勒成像能直接观察房室瓣环的运动,能精确地反映GDM孕妇及胎儿心脏功能受损的状况。Objective To evaluate the cardiac function of pregnant women with gestational diabetes and fetuses by tissue Doppler imaging. Methods Routine cardiac parameters and myocardial motion velocities of four sites of atrioventricular valve ring were detected in 50 pregnant women with gestational diabetes and their fetuses （the diabetes group） as well as 50 healthy pregnant women and their fetuses （the control group） by tissue Doppler imaging. Results The myocardial thickness of the women in the diabetes group was significantly larger than that in the control groups （P〈0.05）. The increase of myocardial thickness was extremely obvious in the late trimester of pregnancy. The Sm, Em and Am of fetuses were significantly lower in the diabetes group than the control group, with statistically significant difference （P〈0.05）, and the EF were significantly higher （P〈0.05）. The Sm and Em of myocardial motion velocities were significantly lower in the diabetes group than the control group, and the Am were significantly higher （P〈0.05）. The decrease of pregnant women had positive correlation with the decrease of the Em of fetuses （r=0.79, P〈0.05）. The increase of Am of regnant women showed positive correlation with the increase of the Am of fetuses （r=0.77, P〈0.05）. Conclusion Tissue Doppler imaging can reflect the cardiac function of the pregnant women with gestational diabetes and their fetuses.

关 键 词：组织多普勒成像 房室瓣环平面 心脏功能 孕妇 胎儿 妊娠糖尿病 

分 类 号：R714.256[医药卫生—妇产科学]