青紫合剂中紫草有效成分提取的最佳工艺研究  

The Study of Optimum Extract Method of Effective Components in Zi Cao of Qing Zi Mixture

作　　者：王晓玲[1] 张艳菊[1] 陈博[1] 

机构地区：[1]首都医科大学附属北京儿童医院,北京100045

出　　处：《现代中药研究与实践》2013年第1期48-49,共2页Research and Practice on Chinese Medicines

基　　金：北京市教委首都中医药与护理科研专项;课题名称:"青紫合剂"的制剂工艺改造与新剂型的开发;课题编号:1000170846

摘　　要：目的优选紫草中有效成分羟基萘醌总色素的最佳提取工艺。方法通过L9(34)正交试验法,以药材中羟基萘醌总色素的质量分数为评价指标,考察提取温度、溶剂浓度及提取时间3个因素,每个因素选取3个水平进行试验。结果最佳提取工艺为95%乙醇,65℃水浴温浸4小时。结论优选得到的工艺稳定、合理、可行。Objective To investigate the influential factors of extract method of Hydroxy beta quinine in Zi Cao, Method Selecting temperature, alcohol concentration and extracting time as influential factors to make L9（34） Orthogonal test. Result The optimal method of extract of Hydroxy beta quinine in Zi Cao was 95% alcohol, 65 ~C water bath soak for 4 hours. Conclusion The optimal extract method was stable, feasible and reasonable.

关 键 词：青紫合剂 紫草 提取工艺 正交试验 

分 类 号：R284.2[医药卫生—中药学]