子痫前期胰岛素抵抗相关因素研究进展  

Study Progress of Insulin Resistance in Preeclampsia

作　　者：曹慧芳[1] 孙敬霞[1] 吴春凤[1] 林洋[1] 杨欣璐[1] 

机构地区：[1]哈尔滨医科大学第一附属医院,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2013年第5期980-982,共3页Progress in Modern Biomedicine

摘　　要：子痫前期是影响孕、产妇发病率和死亡率的重要原因,但是其发病机制目前仍未完全阐明。胰岛素抵抗在子痫前期临床表现出现之前即可被检测到,并参与其发生发展。近来,一些研究认为视黄醇结合蛋白4,同型半胱氨酸等均与胰岛素抵抗相关,并参与子痫前期的发病机制。本文就相关研究进展作一综述。Despite being the leading cause of maternal death and perinatal morbidity,the mechanisms responsible for the pathogenesis of preeclampsia have not been completely understood.Insulin resistance has been observed before the onset of preeclampsia,and is implicated in its pathophysiology.Recently,many studies suggested that there＇s a significant correlation between Retinol-binding protein 4（RBP4） and plasma homocysteine levels with insulin resistance in women with preeclampsia.This article reviewed related progress.

关 键 词：子痫前期 胰岛素抵抗 视黄醇结合蛋白4 同型半胱氨酸 

分 类 号：R714.244[医药卫生—妇产科学]