急性药物性肝炎56例临床分析  

作　　者：赵迪[1] 杜鹏程[1] 顾世玉[1] 张帮杰[1] 

机构地区：[1]新乡医学院第三附属医院消化科,河南新乡453000

出　　处：《中国社区医师（医学专业）》2013年第7期62-63,共2页

摘　　要：目的:分析急性药物性肝病的病因、临床特点及提高临床医师对该病的认识。方法:回顾性分析56例急性药物性肝炎,对其病因及临床特点进行分析。结果:导致急性药物性肝炎药物以抗结核药物最常见,占26.8%;其次,中药占23.2%;抗生素类药物占17.8%。临床类型中肝细胞损伤型占48.2%;胆汁瘀滞型占41.15%;混合型占14.2%。结论:急性药物性肝炎可由多种药物引起,及时停用损肝药物,坚持合理用药,注意药物的不良反应。Objective ： To the etiology, clinical characteristics and improve the understand- ing of acute drug - induced liver disease. Methods： We investigated the causes, inci- dence and clinical characteristics of drug - induced liver disease in 68 cases retrospec- tively. Results：The most common agent to induce liver disease was antitubercular drug 26.8% , the second was traditional Chinese medicine 23.2%, the third was antibiotics 14.2%. There were 48.2% , cases of liver cell injury 41.5% , cases of cholestasis and 14.2% mixed cases. Conclusion： Almost all agents used in clinic may cause liver dis- ease. The principal management for the dis- ease is discontinuation of the suspected drugs.

关 键 词：药物肝病急性药物性肝炎 

分 类 号：R971.1[医药卫生—药品]