静息态功能磁共振成像观察右侧突发性聋患者听觉皮层的功能连接  

Functional connectivity of resting-state functional magnetic resonance imaging observation of the right side of the auditory cortex of sudden deafness

作　　者：朱新[1] 黄志纯[1] 刘斌[2] 杨明[2] 季慧[1] 

机构地区：[1]东南大学附属中大医院耳鼻咽喉-头颈外科,南京210009 [2]东南大学附属中大医院放射科

出　　处：《临床耳鼻咽喉头颈外科杂志》2013年第7期340-343,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金面上项目(No:30970808);南京市科技发展计划项目(No:7990000011);东南大学高校基本科研业务费专项资金(No:3290001504)

摘　　要：目的:利用静息态功能磁共振成像(fMRI)功能连接的方法观察右侧突发性聋患者听觉皮层与脑的正相关的功能连接。方法:选取12例右侧突发性聋患者进行静息态fMRI数据采集,用功能连接的方法观察右侧突发性聋患者左右大脑听觉皮层与脑区不同的正相关功能连接脑图,同时匹配正常听力组比较其差异。结果:当右侧突发性聋患者的有效数据分别以双侧AⅠ区为种子点时,正激活的脑网络主要包含双侧颞横回、颞上回、岛叶、扣带回及辅助运动区,正激活的脑网络类似于正常人,但两者之间有差别。结论:右侧耳聋以AⅠ区为种子点的听觉系统的功能连接仍主要局限于听觉系统之内,但是局部听觉皮层可发生功能重组。Objective：Positively related to functional connectivity using resting state fMRI functional connectivity method to observe the right of sudden deafness of auditory cortex in patients with brain.Method：We selected the right side of the 12 cases of patients with sudden deafness resting state fMRI data acquisition,positive correlation function for the observation about the right of sudden deafness patients using the method of functional connectivity brain auditory cortex and the brain regions to connect brain map,and matched the normal hearing group the difference.Result：The right side of sudden deafness in patients with valid data for the seed point of AⅠbilateral,The brain was activated network included bilateral transverse gyrus,superior temporal gyrus,insula,cingulate gyrus and supplementary motor area.Brain networks were activated like a normal person,but there were differences between the two.Conclusion：The right side of the deafness of A Ⅰseed point the functional connectivity of the auditory system is still mainly confined to the auditory system,but the local auditory cortex functional reorganization occurs.

关 键 词：听觉皮层 静息态 功能连接 听觉丧失 突发性 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]