听力图正常耳鸣患者的隐匿性听力损失:耳鸣起源的启示  

Hidden hearing loss in tinnitus patients with normal audiograms:implications for the origin of tinnitus

作　　者：熊浩[1,2] 陈玲[1,2] 杨海弟[1,2] 李湘辉[1,2] 邱泽恒[1,2] 黄夏茵[1,2] 郑亿庆[1,2] 

机构地区：[1]中山大学孙逸仙纪念医院耳鼻咽喉科 [2]中山大学听力与言语研究所,广州510120

出　　处：《临床耳鼻咽喉头颈外科杂志》2013年第7期362-365,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金资助项目(No:81170921;81200743)

摘　　要：目的:通过分析听力图正常耳鸣患者听性脑干反应(ABR)的特点检测可能存在的隐匿性听力损失,探讨耳鸣的起源。方法:对2010-2012年因单纯性耳鸣就诊于我院的40例患者与15例正常对照者进行纯音听阈、ABR听阈、Ⅰ波及Ⅴ波波幅的检测,并分析其结果。结果:耳鸣患者纯音听阈及ABR阈值与正常对照者无明显差异,但耳鸣患者ABRⅠ波波幅下降,Ⅴ波波幅则恢复正常水平。结论:听力图正常的耳鸣患者在初级听神经水平存在隐匿性听力损失,脑干水平的稳态维持机制可能是产生耳鸣的基础。Objective：To investigate hidden hearing loss in tinnitus patients with normal audiograms by means of auditory brainstem response（ABR） and explore the origin of tinnitus.Method：Pure tone thresholds,ABR thresholds,amplitude of wave Ⅰ and wave Ⅴ of ABR were analyzed in 40 tinnitus patients and 15 controls.Result：There was no significantly difference in pure tone thresholds and ABR thresholds between those tinnitus patients and controls while a reduced amplitude of wave Ⅰ and normal amplitude of wave Ⅴ of ABR in the tinnitus patients became evident.Conclusion：Tinnitus patients with normal audiograms have hidden hearing loss at the level of primary auditory nerve and the generation of tinnitus is likely attributed to a homeostatic response of neurons in brainstem.

关 键 词：耳鸣 纯音测听 听性脑干反应 听力损失 

分 类 号：R764.04[医药卫生—耳鼻咽喉科]