检测N末端B型利钠肽原评价双下肢浮肿在老年人高血压慢性心力衰竭诊断中的价值  

The value of the N terminal b-type natriuretic peptide original test for assessing double lower limbs swelling in the diagnosis of chronic heart failure in the elderly hypertension

作　　者：吴自昌 蔡杰 王文敏 

机构地区：[1]中山市大涌医院急诊科,广东省中山528476 [2]中山市大涌医院内科,广东省中山528476 [3]中山市板芙医院内科

出　　处：《中国基层医药》2013年第8期1134-1136,共3页Chinese Journal of Primary Medicine and Pharmacy

基　　金：广东省中山市卫生局医学科研立项课题（J2011207）

摘　　要：目的探讨老年高血压慢性心力衰竭患者中双下肢浮肿与N末端B型利钠肽原（NT—proBNP）的关系及在鉴别诊断中的价值。方法在因高血压并呼吸困难住院的301例老年患者中，以220ng／L为NT-proBNP异常标准界定值，比较双下肢浮肿与NT-proBNP水平及心力衰竭的相互关系。结果双下肢浮肿对NT-proBNP水平升高阳性预测值为90．3％，阴性预测值为42．1％，敏感性74．4％，特异性80．0％；对心力衰竭的敏感性86．4％，特异性78％。双下肢浮肿与NT-proBNP及心力衰竭显著相关。结论在老年高血压慢性心力衰竭患者中双下肢浮肿预测心力衰竭具备与NT-proBNP相似的价值。Objective Discuss elderly hypertension of chronic heart failure among the edema of lower limbs and the N end of b-type natriuretic peptide（NT-proBNP） formerly relationship and its value in differential diagnosis. Methods Hospitalized for high blood pressure and breathing difficulties in 301 cases of elderly patients, with 220ng/L for the NT-proBNP exception standard defines value, and comparing the edema of lower limbs and the NT- proBNP levels and heart failure. Results In the elderly hypertension of chronic heart failure population of double lower limbs swelling predict heart failure with NT-proBNP similar value. Conclusion Elevated levels of double lower limbs swelling in the NT-proBNP positive predictive value was 90.3 %, negative predictive value was 42.1%, sensitivity 74.4%, specificity 80.0% ; On heart failure of sensitivity 86.4%, specificity 78%. The edema of lower limbs were significantly associated with NT-proBNP and heart failure.

关 键 词：下肢浮肿 N末端B型利钠肽原 高血压 心力衰竭 老年人 

分 类 号：R541.6[医药卫生—心血管疾病]