实验动物屏障系统利旧改造及环境控制效果分析  

Laboratory Animal Barrier System Renovation and Environmental Control Effect Analysis

作　　者：潘劼[1] 张杰[1] 米本中[1] 杨根岭[2] 谭冬梅[2] 杨青 胡娟[1] 樵星芳[1] 

机构地区：[1]重庆市中药研究院,重庆400065 [2]重庆医科大学,重庆400016 [3]重庆展业空调净化工程有限公司,重庆400039

出　　处：《四川动物》2013年第2期289-291,共3页Sichuan Journal of Zoology

基　　金：重庆市科委资助项目(cstc;2009AC5205;cstc;2011ggC0030-27);科技部项目<重庆创新药物孵化基地实验动物服务平台>2010ZX09401-306-1-6

摘　　要：对使用年限超过5年的实验动物屏障系统进行利旧改造,并分析改造后的环境控制效果。在原有基础上对实验动物屏障的排风、空调、土建、监控系统等进行了利旧改造,改造后各项环境指标均符合规范要求,且稳定性得到了很好改善,能耗及故障发生频率显著降低。KM小鼠、SD大鼠繁殖性能均有所增强,饲料利用率提高。在实验动物屏障系统改造过程中将利旧、新技术运用与实现微环境控制进行有机结合,使屏障系统长期高效运转并确保实验动物生产质量。This study aimed to transform laboratory animal barrier system which used for more than 5 years,and to analyze environment control efficiency.After the rebuild of the ventilation system,conditioning system,civil engineering system,and monitoring system of laboratory animal barrier system based on old equipment and components,environmental indicators catch up with the standard requirements,and the stability was improved,energy consumption and the failure occurrence frequency significantly reduced,reproductive performance and feed conversion efficiency of KM mice and SD rats were both enhanced.The combination of laboratory animal barrier system rebuild,new technologies and microenvironment control technology in laboratory animal barrier system transformation process,would be beneficial for long-term performance and the quality of laboratory animal production.

关 键 词：SPF级屏障系统 实验动物 系统改造 环境控制 

分 类 号：Q95-331[生物学—动物学]